典型文献
Highly sensitive electrochemical determination of rutin based on the synergistic effect of 3D porous carbon and cobalt tungstate nanosheets
文献摘要:
Rutin,a flavonoid found in fruits and vegetables,is a potential anticancer compound with strong anti-cancer activity.Therefore,electrochemical sensor was developed for the detection of rutin.In this study,CoWO4 nanosheets were synthesized via a hydrothermal method,and porous carbon(PC)was prepared via high-temperature pyrolysis.Successful preparation of the materials was confirmed,and character-ization was performed by transmission electron microscopy,scanning electron microscopy,and X-ray photoelectron spectroscopy.A mixture of PC and CoWO4 nanosheets was used as an electrode modifier to fabricate the electrochemical sensor for the electrochemical determination of rutin.The 3D CoWO4 nanosheets exhibited high electrocatalytic activity and good stability.PC has a high surface-to-volume ratio and superior conductivity.Moreover,the hydrophobicity of PC allows large amounts of rutin to be adsorbed,thereby increasing the concentration of rutin at the electrode surface.Owing to the syn-ergistic effect of the 3D CoWO4 nanosheets and PC,the developed electrochemical sensor was employed to quantitively determine rutin with high stability and sensitivity.The sensor showed a good linear range(5-5000 ng/mL)with a detection limit of O.45 ng/mL.The developed sensor was successfully applied to the determination of rutin in crushed tablets and human serum samples.
文献关键词:
中图分类号:
作者姓名:
Guangjun Feng;Yang Yang;Jiantao Zeng;Jun Zhu;Jingjian Liu;Lun Wu;Zhiming Yang;Guanyi Yang;Quanxi Mei;Qinhua Chen;Fengying Ran
作者机构:
Shenzhen Baoan Authentic TCM Therapy Hospital,Shenzhen,518101,China;Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine,Shenzhen,518101,China;Sinopharm Dongfeng General Hospital,Hubei University of Medicine,Shiyan,Hubei,442008,China
文献出处:
引用格式:
[1]Guangjun Feng;Yang Yang;Jiantao Zeng;Jun Zhu;Jingjian Liu;Lun Wu;Zhiming Yang;Guanyi Yang;Quanxi Mei;Qinhua Chen;Fengying Ran-.Highly sensitive electrochemical determination of rutin based on the synergistic effect of 3D porous carbon and cobalt tungstate nanosheets)[J].药物分析学报(英文),2022(03):453-459
A类:
B类:
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AB值:
0.516303
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