典型文献
Recent advance of fluorescent probes for detection of drug-induced liver injury markers
文献摘要：
Drug-induced liver injury(DILI)is a common and serious adverse drug reaction.At present,DILI is per-fectly diagnozed in clinical settings using Roussel Uclaf causality assessment method(RUCAM)in its orig-inal version published 1993 and its updated version published 2016,well established worldwide as a di-agnostic algorithm with a high sensitivity and specificity.Nevertheless,the search for additional detection methods supporting RUCAM continues.In recent years,with the development of optical imaging technol-ogy,fluorescent probes have gradually shown great advantages in the detection and diagnosis of DILI markers such as high sensitivity,anti-interference,real-time monitoring and non-invasive measurement.In this review,the recent advances of fluorescent probes for evaluation of DILI in experimental studies were summarized according to various markers of DILI.We believe that learning about the design and practical application of these probes will contribute to the further development of detection sensors for DILI markers.
文献关键词：
中图分类号：
作者姓名：
Dongqin Sun;Zhenzhen Chen;Jiali Hu;Huajin Zeng;Lingbo Qu;Ran Yang
作者机构：
School of Pharmaceutical Sciences,Zhengzhou University,Zhengzhou 450001,China;The College of Chemistry,Zhengzhou University,Zhengzhou 450001,China
文献出处：
引用格式：
[1]Dongqin Sun;Zhenzhen Chen;Jiali Hu;Huajin Zeng;Lingbo Qu;Ran Yang-.Recent advance of fluorescent probes for detection of drug-induced liver injury markers)[J].中国化学快报（英文版）,2022(10):4478-4494
A类：
diagnozed
B类：
Recent,fluorescent,probes,detection,drug,induced,liver,injury,markers,Drug,DILI,common,serious,adverse,reaction,At,present,fectly,clinical,settings,using,Roussel,Uclaf,causality,assessment,RUCAM,its,orig,inal,version,published,updated,well,established,worldwide,agnostic,algorithm,high,sensitivity,specificity,Nevertheless,search,additional,methods,supporting,continues,In,recent,years,development,optical,imaging,technol,ogy,have,gradually,shown,great,advantages,diagnosis,such,anti,interference,real,monitoring,invasive,measurement,this,review,advances,evaluation,experimental,studies,were,summarized,according,various,We,believe,that,learning,about,design,practical,application,these,will,contribute,further,sensors
AB值：
0.625275
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