Zn-1.0Cu-0.5Ca(TA15)alloy has shown promising characteristics of enhanced mechanical properties and biodegradability for absorbable cardiovascular stents,endovascular devices,and wound closure devices applications.In this study,the TA15 alloy for bioabsorbable biomedical applications is investigated.In the conventionally cast TA15(TA15-C)alloy,CaZn13 phase are present as a large dendritic network with an average size of 73.25±112.84 μm.Hot rolling of the TA15-C alloy has broken the long and dendritic network of the CaZn13 phases,however,the refined phases are observed as segregations and the distri-bution is non-uniform.These segregated CaZn13 suffered heavy localised corrosion which lead to poor mechanical properties in the as-fabricated condition and after biodegradation.Ultrasonic treatment(UST)during casting is identified as an effective technique for the refinement and redistribution of CaZn13 par-ticles in TA15 alloy,which successfully reduce the size of the CaZn13 phase to 10.91±4.65 μm in the as-solidified condition.After hot rolling,the UST processed TA15(TA15-UST)shows improved mechanical properties due to grain refinement and the reduction in microstructural defects,i.e.the broken CaZn13 phase.Results of 8-week immersion corrosion tests showed that both alloys possess very similar corro-sion rate.However,TA15-UST has markedly improved corrosion homogeneity compared to TA15-N which favours the retention of mechanical properties even after prolonged exposure to physiological fluids.

Nan Yang;Nagasivamuni Balasubramani;Jeffrey Venezuela;Helle Bielefeldt-Ohmann;Rachel Allavena;Sharifah Almathami;Matthew Dargusch

Queensland Centre for Advanced Materials Processing and Manufacturing(AMPAM)School of Mechanical and Mining Engineering,The University of Queensland,Advanced Engineering Building,Bld 49,Staff House Rd.,St Lucia,QLD 4072,Australia;School of Veterinary Science,The University of Queensland,Gatton,QLD 4343,Australia;School of Chemistry and Molecular Biosciences,The University of Queensland,QLD 4072,Australia

材料科学技术（英文版）

[1]Nan Yang;Nagasivamuni Balasubramani;Jeffrey Venezuela;Helle Bielefeldt-Ohmann;Rachel Allavena;Sharifah Almathami;Matthew Dargusch-.Microstructure refinement in biodegradable Zn-Cu-Ca alloy for enhanced mechanical properties,degradation homogeneity,and strength retention in simulated physiological condition)[J].材料科学技术（英文版）,2022(30):1-14

bioabsorbable,CaZn13,favours

Microstructure,refinement,biodegradable,enhanced,mechanical,properties,homogeneity,strength,retention,simulated,physiological,condition,0Cu,5Ca,TA15,shown,promising,characteristics,biodegradability,cardiovascular,stents,endovascular,devices,wound,closure,applications,In,this,study,biomedical,investigated,conventionally,present,large,dendritic,network,average,size,Hot,rolling,broken,phases,however,refined,observed,segregations,uniform,These,segregated,suffered,heavy,localised,corrosion,which,lead,poor,fabricated,after,biodegradation,Ultrasonic,treatment,UST,during,casting,identified,effective,technique,redistribution,ticles,successfully,reduce,solidified,After,hot,processed,shows,improved,due,grain,reduction,microstructural,defects,Results,week,immersion,tests,showed,that,both,alloys,possess,very,similar,rate,However,markedly,compared,even,prolonged,exposure,fluids

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