典型文献
Advances in lung cancer screening and early detection
文献摘要：
Lung cancer is associated with a heavy cancer-related burden in terms of patients' physical and mental health worldwide. Two randomized controlled trials, the US-National Lung Screening Trial (NLST) and Nederlands-Leuvens Longkanker Screenings Onderzoek (NELSON), indicated that low-dose CT (LDCT) screening results in a statistically significant decrease in mortality in patients with lung cancer, LDCT has become the standard approach for lung cancer screening. However, many issues in lung cancer screening remain unresolved, such as the screening criteria, high false-positive rate, and radiation exposure. This review first summarizes recent studies on lung cancer screening from the US, Europe, and Asia, and discusses risk-based selection for screening and the related issues. Second, an overview of novel techniques for the differential diagnosis of pulmonary nodules, including artificial intelligence and molecular biomarker-based screening, is presented. Third, current explorations of strategies for suspected malignancy are summarized. Overall, this review aims to help clinicians understand recent progress in lung cancer screening and alleviate the burden of lung cancer.
文献关键词：
中图分类号：
作者姓名：
Caichen Li;Huiting Wang;Yu Jiang;Wenhai Fu;Xiwen Liu;Ran Zhong;Bo Cheng;Feng Zhu;Yang Xiang;Jianxing He;Wenhua Liang
作者机构：
Department of Thoracic Oncology and Surgery,the First Affiliated Hospital of Guangzhou Medical University,China National Center for Respiratory Medicine,China State Key Laboratory of Respiratory Disease&National Clinical Research Center for Respiratory Disease,Guangzhou Institute of Respiratory Health,Guangzhou 510120,China;Dongguan Affiliated Hospital of Southern Medical University,Dongguan People Hospital,Dongguan 523059,China;Department of Internal Medicine,Detroit Medical Center Sinai-Grace Hospital,Detroit,Michigan 48235,USA;Department of Thoracic Surgery,Nanfang Hospital of Southern Medical University,Guangzhou 510515,China;Department of Oncology,the First People's Hospital of Zhaoqing,Zhaoqing 526020,China
文献出处：
引用格式：
[1]Caichen Li;Huiting Wang;Yu Jiang;Wenhai Fu;Xiwen Liu;Ran Zhong;Bo Cheng;Feng Zhu;Yang Xiang;Jianxing He;Wenhua Liang-.Advances in lung cancer screening and early detection)[J].癌症生物学与医学（英文版）,2022(05):591-608
A类：
NLST,Nederlands,Leuvens,Longkanker,Screenings,Onderzoek,NELSON
B类：
Advances,lung,cancer,screening,early,detection,Lung,associated,heavy,related,burden,terms,patients,physical,mental,health,worldwide,Two,randomized,controlled,trials,US,National,Trial,indicated,that,low,dose,LDCT,results,statistically,significant,decrease,mortality,has,become,standard,approach,However,many,issues,remain,unresolved,such,criteria,high,false,positive,radiation,exposure,This,review,first,summarizes,recent,studies,from,Europe,Asia,discusses,risk,selection,Second,overview,novel,techniques,differential,diagnosis,pulmonary,nodules,including,artificial,intelligence,molecular,biomarker,presented,Third,current,explorations,strategies,suspected,malignancy,are,summarized,Overall,this,aims,help,clinicians,understand,progress,alleviate
AB值：
0.572848
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