典型文献
Role of IL?17 family cytokines in the progression of IPF from inflammation to fibrosis
文献摘要：
Idiopathic pulmonary fibrosis (IPF) is a fatal chronic interstitial lung disease with no established treatment and is characterized by progressive scarring of the lung tissue and an irreversible decline in lung function. Chronic inflammation has been demonstrated to be the pathological basis of fibrosis. Emerging studies have revealed that most interleukin-17 (IL-17) isoforms are essential for the mediation of acute and chronic inflammation via innate and adaptive immunity. Overexpression or aberrant expression of IL-17 cytokines contributes to various pathological outcomes, including the initiation and exacerbation of IPF. Here, we aim to provide an overview of IL-17 family members in the pathogenesis of IPF.
文献关键词：
中图分类号：
作者姓名：
Yun?Juan Nie;Shuo?Hua Wu;Ying?Hua Xuan;Gen Yan
作者机构：
Department of Basic Medicine,Wuxi School of Medicine,Jiangnan University,Wuxi 214000,Jiangsu,China;Department of Radiology,the Second Affiliated Hospital,Medical College of Shantou University,Shantou 515000,Guangdong,China;Department of Basic Medicine,Xiamen Medical College,Xiamen 361000,Fujian,China;Department of Radiology,the Second Affiliated Hospital of Xiamen Medical College,Xiamen 361000,Fujian,China
文献出处：
引用格式：
[1]Yun?Juan Nie;Shuo?Hua Wu;Ying?Hua Xuan;Gen Yan-.Role of IL?17 family cytokines in the progression of IPF from inflammation to fibrosis)[J].军事医学研究（英文）,2022(05):618-627
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Role,family,cytokines,progression,IPF,from,inflammation,fibrosis,Idiopathic,pulmonary,fatal,chronic,interstitial,lung,disease,no,established,treatment,characterized,by,progressive,scarring,tissue,irreversible,decline,function,Chronic,has,been,demonstrated,pathological,basis,Emerging,studies,have,revealed,that,most,interleukin,isoforms,are,essential,mediation,acute,via,innate,adaptive,immunity,Overexpression,aberrant,contributes,various,outcomes,including,initiation,exacerbation,Here,we,aim,provide,overview,members,pathogenesis
AB值：
0.660075
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