典型文献
The roles of exosomal immune checkpoint proteins in tumors
文献摘要:
Targeting immune checkpoints has achieved great therapeutic effects in the treatment of early-stage tumors. However, most patients develop adaptive resistance to this therapy. The latest evidence demonstrates that tumor-derived exosomes may play a key role in systemic immune suppression and tumor progression. In this article, we highlight the role of exosomal immune checkpoint proteins in tumor immunity, with an emphasis on programmed death ligand 1 (PD-L1) and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), as well as emerging evidence on roles of T cell immunoglobulin-3 (TIM-3), arginase 1 (ARG1), and estrogen receptor binding fragment-associated antigen 9 (EBAG9) expressed by exosomes.
文献关键词:
中图分类号:
作者姓名:
Cheng Xing;Heng Li;Rui‑Juan Li;Le Yin;Hui‑Fang Zhang;Zi‑Neng Huang;Zhao Cheng;Ji Li;Zhi‑Hua Wang;Hong‑Ling Peng
作者机构:
Department of Hematology,The Second Xiangya Hospital,Central South University,Changsha 410011,China;Institute of Molecular Hematology,Central South University,Changsha 410011,China;Hunan Key Laboratory of Tumor Models and Individualized Medicine,Changsha 410011,China
文献出处:
引用格式:
[1]Cheng Xing;Heng Li;Rui‑Juan Li;Le Yin;Hui‑Fang Zhang;Zi‑Neng Huang;Zhao Cheng;Ji Li;Zhi‑Hua Wang;Hong‑Ling Peng-.The roles of exosomal immune checkpoint proteins in tumors)[J].军事医学研究(英文),2022(03):365-375
A类:
EBAG9
B类:
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AB值:
0.64253
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