首站-论文投稿智能助手
典型文献
The roles of exosomal immune checkpoint proteins in tumors
文献摘要:
Targeting immune checkpoints has achieved great therapeutic effects in the treatment of early-stage tumors. However, most patients develop adaptive resistance to this therapy. The latest evidence demonstrates that tumor-derived exosomes may play a key role in systemic immune suppression and tumor progression. In this article, we highlight the role of exosomal immune checkpoint proteins in tumor immunity, with an emphasis on programmed death ligand 1 (PD-L1) and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), as well as emerging evidence on roles of T cell immunoglobulin-3 (TIM-3), arginase 1 (ARG1), and estrogen receptor binding fragment-associated antigen 9 (EBAG9) expressed by exosomes.
文献关键词:
作者姓名:
Cheng Xing;Heng Li;Rui‑Juan Li;Le Yin;Hui‑Fang Zhang;Zi‑Neng Huang;Zhao Cheng;Ji Li;Zhi‑Hua Wang;Hong‑Ling Peng
作者机构:
Department of Hematology,The Second Xiangya Hospital,Central South University,Changsha 410011,China;Institute of Molecular Hematology,Central South University,Changsha 410011,China;Hunan Key Laboratory of Tumor Models and Individualized Medicine,Changsha 410011,China
引用格式:
[1]Cheng Xing;Heng Li;Rui‑Juan Li;Le Yin;Hui‑Fang Zhang;Zi‑Neng Huang;Zhao Cheng;Ji Li;Zhi‑Hua Wang;Hong‑Ling Peng-.The roles of exosomal immune checkpoint proteins in tumors)[J].军事医学研究(英文),2022(03):365-375
A类:
EBAG9
B类:
roles,exosomal,immune,proteins,tumors,Targeting,checkpoints,achieved,great,therapeutic,effects,treatment,early,stage,However,most,patients,develop,adaptive,resistance,this,therapy,latest,evidence,demonstrates,that,derived,exosomes,may,play,key,systemic,suppression,progression,In,article,highlight,immunity,emphasis,programmed,death,ligand,L1,cytotoxic,lymphocyte,associated,antigen,CTLA,well,emerging,cell,immunoglobulin,TIM,arginase,ARG1,estrogen,receptor,binding,fragment,expressed,by
AB值:
0.64253
相似文献
Defined tumor antigen-specific T cells potentiate personalized TCR-T cell therapy and prediction of immunotherapy response
Jingjing He;Xinxin Xiong;Han Yang;Dandan Li;Xuefei Liu;Shuo Li;Shuangye Liao;Siyu Chen;Xizhi Wen;Kuai Yu;Lingyi Fu;Xingjun Dong;Kaiyu Zhu;Xiaojun Xia;Tiebang Kang;Chaochao Bian;Xiang Li;Haiping Liu;Peirong Ding;Xiaoshi Zhang;Zhenjiang Liu;Wende Li;Zhixiang Zuo;Penghui Zhou-State Key Laboratory of Oncology in Southern China,Collaborative Innovation Center for Cancer Medicine,Sun Yat-sen University Cancer Center,Guangzhou,China;Guangdong Provincial People's Hospital,Guangdong Academy of Medical Sciences,Guangzhou,China;Guangdong Laboratory Animals Monitoring Institute,Guangdong Key Laboratory of Laboratory Animals,Guangzhou,China;Guangzhou Finelmmune Biotechnology Co.,LTD,Guangzhou,China
Abrogation of HnRNP L enhances anti-PD-1 therapy efficacy via diminishing PD-L1 and promoting CD8+T cell-mediated ferroptosis in castration-resistant prostate cancer
Xumin Zhou;Libin Zou;Hangyu Liao;Junqi Luo;Taowei Yang;Jun Wu;Wenbin Chen;Kaihui Wu;Shengren Cen;Daojun Lv;Fangpeng Shu;Yu Yang;Chun Li;Bingkun Li;Xiangming Mao-Department of Urology,Zhujiang Hospital,Southern Medical University,Guangzhou 510280,China;Second Department of Hepatobiliary Surgery,Zhujiang Hospital,Southern Medical University,Guangzhou 510280,China;Department of Urology,Minimally Invasive Surgery Center,the First Affiliated Hospital of Guangzhou Medical University,Guangzhou 510120,China;Department of Urology,Guangzhou Women and Children's Medical Center,Guangzhou Medical University,Guangzhou 510623,China;Department of Urology,Peking University Shenzhen Hospital,Shenzhen 518036,China;Nursing Department,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China
Targeting HMGB1 for the treatment of sepsis and sepsis-induced organ injury
Chao Deng;Lin Zhao;Zhi Yang;Jia-jia Shang;Chang-yu Wang;Ming-zhi Shen;Shuai Jiang;Tian Li;Wen-cheng Di;Ying Chen;He Li;Ye-dong Cheng;Yang Yang-Xi'an Key Laboratory of Cardiovascular and Cerebrovascular Diseases,Xi'an No.3 Hospital,School of Life Sciences and Medicine,Northwest University,Xi'an 710021,China;Department of Orthopaedics,Huaian Medical District of Jingling Hospital,Medical School of Nanjing University,Huaian 213001,China;Department of Cardiovascular Surgery,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China;Department of Cardiovascular Surgery,Xijing Hospital,The Fourth Military Medical University,Xi'an 710032,China;Key Laboratory of Resource Biology and Biotechnology in Western China,Ministry of Education.Life of Sciences,Northwest University,Xi'an 710021,China;Department of Cardiology,Xi'an No.3 Hospital,School of Life Sciences and Medicine,Northwest University,Xi'an 710021,China;Hainan Hospital of PLA General Hospital,The Second School of Clinical Medicine,Southern Medical University,Sanya 572013,China;National Clinical Research Center for Infectious Diseases,Shenzhen Third People's Hospital,Southern University of Science and Technology,Shenzhen 518100,China;Department of Hematology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China
机标中图分类号,由域田数据科技根据网络公开资料自动分析生成,仅供学习研究参考。