As a group of nonspecific inflammatory diseases affecting the intestine, inflammatory bowel disease (IBD) exhibits the characteristics of chronic recurring inflammation, and was proven to be increasing in inci-dence (Kaplan, 2015). IBD induced by genetic back-ground, environmental changes, immune functions, microbial composition, and toxin exposures (Sasson et al., 2021) primarily includes ulcerative colitis (UC) and Crohn's disease (CD) with complicated clinical symptoms featured by abdominal pain, diarrhea, and even blood in stools (Fan et al., 2021; Huang et al., 2021). UC is mainly limited to the rectum and the colon, while CD usually impacts the terminal ileum and colon in a discontinuous manner (Ordás et al., 2012;Panés and Rimola, 2017). In recent years, many studies have suggested the lack of effective measures in the diagnosis and treatment of IBD, prompting an urgent need for new strategies to understand the mechanisms of and offer promising therapies for IBD.

Yuting XU;Li ZHANG;Dickson Kofi Wiredu OCANSEY;Bo WANG;Yilin HOU;Rong MEI;Yongmin YAN;Xu ZHANG;Zhaoyang ZHANG;Fei MAO

Key Laboratory of Medical Science and Laboratory Medicine of Jiangsu Province,School of Medicine,Jiangsu University,Zhenjiang 212013,China;Nanjing Lishui People's Hospital,Zhongda Hospital Lishui Branch,Southeast University,Nanjing 211200,China;Directorate of University Health Services,University of Cape Coast,Cape Coast,Ghana;Department of Gastroenterology,the Second People's Hospital of Zhenjiang,Zhenjiang 212000,China;Clinical Lab,Taicang Hospital of Traditional Chinese Medicine,Suzhou 215400,China

浙江大学学报（英文版）（B辑：生物医学和生物技术）

[1]Yuting XU;Li ZHANG;Dickson Kofi Wiredu OCANSEY;Bo WANG;Yilin HOU;Rong MEI;Yongmin YAN;Xu ZHANG;Zhaoyang ZHANG;Fei MAO-.HucMSC-Ex alleviates inflammatory bowel disease via the lnc78583-mediated miR3202/HOXB13 pathway)[J].浙江大学学报（英文版）（B辑：生物医学和生物技术）,2022(05):423-431,中插12-中插14

HucMSC,lnc78583,miR3202,Sasson,Rimola

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