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典型文献
基于住院儿童患者地高辛有效浓度监测数据的回顾性分析
文献摘要:
目的:回顾性分析住院儿童患者应用地高辛的情况,为临床使用该药提供更准确的有效浓度范围.方法:通过瑞美实验室管理系统,查询收集儿童患者病历,对数据进行统计和分析.结果:共收集病历150份,地高辛血药浓度为0.5~1.5 ng·mL-1治愈率最高(69.5%),0.3 ng·mL-1和0.3~0.5 ng·mL-1浓度范围的治愈率(41.7%)、稳定率(33.3%)和已控制率(25.0%)均相同.男性血药浓度在0.3~0.5、1.5~2.0和>5.0 ng·mL-1的比例高于女性,女性血药浓度在<0.3、0.5~1.5和2.0~5.0 ng·mL-1的比例高于男性;1岁以下患者血药浓度范围在0.3~0.5 ng·mL-1的比例低于1岁以上患者.结论:在实际临床治疗中,儿童患者的地高辛血药浓度低于目标浓度时,也能达到一定的治疗效果.为实现更合理用药,应结合儿童患者实际情况,个体化调整有效血药浓度范围.
文献关键词:
地高辛;儿童;血药浓度;治疗药物监测;疗效
作者姓名:
杨丹;王漪檬;马爱玲;马培志
作者机构:
河南省人民医院药学部,河南 郑州 450003
引用格式:
[1]杨丹;王漪檬;马爱玲;马培志-.基于住院儿童患者地高辛有效浓度监测数据的回顾性分析)[J].中国药物应用与监测,2022(04):226-228,234
A类:
B类:
住院儿童,儿童患者,地高辛,临床使用,该药,有效浓度范围,实验室管理系统,病历,共收,血药浓度,治愈率,稳定率,控制率,目标浓度,更合,合理用药,治疗药物监测
AB值:
0.251378
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