典型文献
Pyroptosis and pyroptosis-inducing cancer drugs
文献摘要：
Pyroptosis,an inflammatory form of lytic cell death,is a type of cell death mediated by the gasdermin(GSDM)protein family.Upon recognizing exogenous or endogenous signals,cells undergo inflammasome assembly,GSDM cleavage,the release of proinflammatory cytokines and other cellular contents,eventually leading to inflammatory cell death.In this review,we discuss the roles of the GSDM family for anti-cancer functions and various antitumor drugs that could activate the pyroptosis pathways.
文献关键词：
中图分类号：
作者姓名：
Fan Yang;Sahana N.Bettadapura;Mark S.Smeltzer;Hua Zhu;Shanzhi Wang
作者机构：
Healthville LLC,Little Rock,AR 72204,USA;Biology Department,University of Arkansas at Little Rock,Little Rock,AR 72204,USA;Department of Microbiology and Immunology,University of Arkansas for Medical Sciences,Little Rock,AR 72205,USA;Department of Surgery,The Ohio State University Wexner Medical Center,Columbus,OH 43210,USA;Chemistry Department,University of Arkansas at Little Rock,Little Rock,AR 72204,USA
文献出处：
引用格式：
[1]Fan Yang;Sahana N.Bettadapura;Mark S.Smeltzer;Hua Zhu;Shanzhi Wang-.Pyroptosis and pyroptosis-inducing cancer drugs)[J].中国药理学报（英文版）,2022(10):2462-2473
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B类：
Pyroptosis,pyroptosis,inducing,cancer,drugs,form,lytic,death,type,mediated,by,gasdermin,GSDM,protein,family,Upon,recognizing,exogenous,endogenous,signals,cells,undergo,inflammasome,assembly,cleavage,release,proinflammatory,cytokines,other,cellular,contents,eventually,leading,In,this,review,we,discuss,roles,functions,various,antitumor,that,could,activate,pathways
AB值：
0.677411
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