典型文献
Clinical characteristics and related risk factors of disease severity in 101 COVID-19 patients hospitalized in Wuhan,China
文献摘要：
Coronavirus disease 2019(COVID-19)broke out in December 2019.Due its high morbility and mortality,it is necessary to summarize the clinical characteristics of COVID-19 patients to provide more theoretical basis for future treatment.In the current study,we conducted a retrospective analysis of the clinical characteristics of COVID-19 patients and explored the risk factors for the severity of illness.A total of 101 COVID-19 patients hospitalized in Leishenshan Hospital(Wuhan,China)was classified into three sub-types:moderate(n=47),severe(n=36),and critical(n=18);their clinical data were collected from the Electronic Medical Record.We showed that among the 101 COVID-19 patients,the median age was 62 years(IQR 51-74);50(49.5％)patients were accompanied by hypertension,while 25(24.8％)and 22(21.8％)patients suffered from diabetes and heart diseases,respectively,with complications.All patients were from Wuhan who had a definite history of exposure to the epidemic area.Multivariate logistic regression analysis revealed that older age,diabetes,chronic liver disease,percentage of neutrophils(N％)＞75％,CRP＞4 mg/L,D-dimer＞0.55 mg/L,IL-2R＞710 U/mL,IL-8＞62 pg/mL,and IL-10＞9.1 pg/mL were independent variables associated with severe COVID-19.In conclusion,we have identified the independent risk factors for the severity of COVID-19 pneumonia,including older age,diabetes,chronic liver disease,higher levels of N％,CRP,D-dimer,IL-2R,IL-8,and IL-10,providing evidence for more accurate risk prediction.
文献关键词：
中图分类号：
作者姓名：
Xue-qing Liu;Shan Xue;Jia-bo Xu;Heng Ge;Qing Mao;Xin-hui Xu;Han-dong Jiang
作者机构：
Department of Respiratory and Critical Care Medicine,Ren Ji Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200001,China;Department of Intensive Infection,Leishenshan Hospital,Wuhan 430212,China;Department of Cardiology,Ren Ji Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200001,China;Department of Neurosurgery,Ren Ji Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200001,China;Department of Emergency,Ren Ji Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200001,China
文献出处：
引用格式：
[1]Xue-qing Liu;Shan Xue;Jia-bo Xu;Heng Ge;Qing Mao;Xin-hui Xu;Han-dong Jiang-.Clinical characteristics and related risk factors of disease severity in 101 COVID-19 patients hospitalized in Wuhan,China)[J].中国药理学报（英文版）,2022(01):64-75
A类：
morbility,Leishenshan
B类：
Clinical,characteristics,related,risk,factors,severity,patients,hospitalized,Wuhan,China,Coronavirus,broke,out,December,Due,its,mortality,necessary,summarize,clinical,provide,more,theoretical,basis,future,treatment,In,current,study,conducted,retrospective,analysis,explored,illness,total,Hospital,was,classified,into,three,sub,types,moderate,severe,critical,their,data,were,collected,from,Electronic,Medical,Record,We,showed,that,among,median,years,IQR,accompanied,by,hypertension,while,suffered,diabetes,heart,diseases,respectively,complications,All,who,had,definite,history,exposure,epidemic,area,Multivariate,logistic,regression,revealed,older,chronic,liver,percentage,neutrophils,dimer,2R,pg,independent,variables,associated,conclusion,have,identified,pneumonia,including,higher,levels,providing,evidence,accurate,prediction
AB值：
0.551795
相似文献
机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
