典型文献
Outcomes of patients awaiting lung transplantation after the implementation of donation after brain death at a single Chinese center
文献摘要：
Voluntary contribution has become the only source of donor lungs in China since 2015.To elaborate the outcomes of patients awaiting lung transplantation(LTx)after the implementation of donation after brain death,we performed a retrospective study that encompassed 205 patients with end-stage lung disease who registered for LTx at Shanghai Pulmonary Hospital from January 1,2015 to January 1,2021.A total of 180 patients were enrolled in the study.The median waiting time was 1.25 months.Interstitial lung disease(ILD)(103/180,57.2％)and chronic obstructive pulmonary disease(COPD)(56/180,31.1％)were the most common diseases in our study population.The mean pulmonary artery pressure(mPAP)of patients in the died-waiting group was higher than that of the survivors(53.29±21.71 mmHg vs.42.11±18.58 mmHg,P=0.002).The mortality of patients with ILD(34/103,33.00％)was nearly twice that of patients with COPD(10/56,17.86％)while awaiting LTx(P=0.041).In the died-waiting group,patients with ILD had a shorter median waiting time than patients with COPD after being listed(0.865 months vs.4.720 months,P=0.030).ILD as primary disease and mPAP＞35 mmHg were two significant independent risk factors for waitlist mortality,with hazard ratios(HR)of 3.483(95％CI 1.311-9.111;P=0.011)and 3.500(95％CI 1.435-8.536;P=0.006).Hence,LTx is more urgently needed in patients with ILD and pulmonary hypertension.
文献关键词：
中图分类号：
作者姓名：
Yuling Yang;Xinnan Xu;Ming Liu;Yanfeng Zhao;Yongmei Yu;Xiaogang Liu;Chang Chen;Gening Jiang;Wenxin He
作者机构：
Department of Thoracic Surgery,Shanghai Pulmonary Hospital,School of Medicine,Tongji University,Shanghai 200092,China;Department of Cardiothoracic Surgery,Zhangzhou Affiliated Hospital of Fujian Medical University,Zhangzhou 363000,China
文献出处：
引用格式：
[1]Yuling Yang;Xinnan Xu;Ming Liu;Yanfeng Zhao;Yongmei Yu;Xiaogang Liu;Chang Chen;Gening Jiang;Wenxin He-.Outcomes of patients awaiting lung transplantation after the implementation of donation after brain death at a single Chinese center)[J].医学前沿,2022(05):760-765
A类：
waitlist
B类：
Outcomes,patients,awaiting,transplantation,after,implementation,donation,brain,death,single,Chinese,center,Voluntary,contribution,has,become,only,source,donor,lungs,China,since,To,elaborate,outcomes,LTx,performed,retrospective,study,that,encompassed,stage,who,registered,Shanghai,Pulmonary,Hospital,from,January,total,were,enrolled,median,was,months,Interstitial,ILD,chronic,obstructive,pulmonary,COPD,most,common,diseases,population,mean,artery,pressure,mPAP,died,group,higher,than,survivors,mmHg,mortality,nearly,twice,while,had,shorter,being,listed,primary,two,significant,independent,risk,factors,hazard,ratios,Hence,more,urgently,needed,hypertension
AB值：
0.480292
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