典型文献
Regulation effect of osteoblasts towards osteocytes by silk fibroin encapsulation
文献摘要：
Herein,the rational design micromilieus involved silk fibroin(SF)-based materials have been used to encapsulate the osteoblasts,forming an extracellular coated shell on the cells,which exhibited the high potential to shift the regulation of osteoblasts to osteocytes by encapsulation cues.SF coating treated cells showed a change in cell morphology from osteoblasts-like to osteocytes-like shape compared with untreated ones.Moreover,the expression of alkaline phosphatase(ALP),collagen I(Col I)and osteocalcin(OCN)further indicated a potential approach for inducing osteoblasts regulation,which typically accelerates calcium deposition and cell calcification,presenting a key role for the SF encapsulation in controlling osteoblasts behavior.This discovery showed that SF-based cell encapsulation could be used for osteoblasts behavior regulation,which offers a great potential to modulate mammalian cells'phenotype involving alternating surrounding cues.
文献关键词：
中图分类号：
作者姓名：
Dandan LUO;Rui ZHANG;Shibo WANG;M.Zubair IQBAL;Ruibo ZHAO;Xiangdong KONG
作者机构：
Institute of Smart Biomedical Materials,School of Materials Science and Engineering,Zhejiang Sci-Tech University,Hangzhou 310018,China;Zhejiang-Mauritius Joint Research Center for Biomaterials and Tissue Engineering,Zhejiang Sci-Tech University,Hangzhou 310018,China;School of Textile Science and Engineering,Zhejiang Sci-Tech University,Hangzhou 310018,China
文献出处：
引用格式：
[1]Dandan LUO;Rui ZHANG;Shibo WANG;M.Zubair IQBAL;Ruibo ZHAO;Xiangdong KONG-.Regulation effect of osteoblasts towards osteocytes by silk fibroin encapsulation)[J].材料学前沿,2022(04):1-13
A类：
micromilieus
B类：
Regulation,effect,osteoblasts,towards,osteocytes,by,silk,fibroin,encapsulation,Herein,rational,design,involved,SF,materials,have,been,used,encapsulate,forming,extracellular,coated,shell,cells,which,exhibited,high,potential,shift,regulation,cues,coating,showed,change,morphology,from,like,shape,compared,untreated,ones,Moreover,expression,alkaline,phosphatase,ALP,collagen,Col,osteocalcin,OCN,further,indicated,approach,inducing,typically,accelerates,calcium,deposition,calcification,presenting,key,role,controlling,behavior,This,discovery,that,could,offers,great,modulate,mammalian,phenotype,involving,alternating,surrounding
AB值：
0.59229
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
