典型文献
Enhanced bioactivity and interfacial bonding strength of Ti3Zr2Sn3Mo25Nb alloy through graded porosity and surface bioactivation
文献摘要：
The gradient porous Ti3Zr2Sn3Mo25Nb(TLM)alloy rods were fabricated through sintering the alloyed powder to a solid core.The porous sample was then modified by a Micro Arc Oxidation(MAO)treat-ment in an electrolyte containing calcium and phosphate,a hydrothermal treatment enabled secondary microporous hydroxyapatite(HA)coating,and a further bone morphogenetic protein-2(BMP-2)loading treatment through immersion and freeze-drying.The treatment led to an orderly secondary microporous coating containing HA nano-particles and evenly distributed BMP-2 in the porous coatings.As a result,osteoblasts could adhere and grow well on the coatings with a high cell adhesion rate and cell functional activity.The in-situ shear testing indicated that the interfacial strength had been enhanced significantly.Improvement of the bond formation and osseointegration with the titanium implant is attributed to in-creased surface area for the cell to attach,creating voids for the cell to grow in,and activating titanium surface by introducing bioactive ingredients such as HA and BMP-2.
文献关键词：
中图分类号：
作者姓名：
Sen Yu;Zhe Yu;Dagang Guo;Hui Zhu;Minghua Zhang;Jianye Han;Zhentao Yu;Yemin Cao;Gui Wang
作者机构：
State Key Laboratory for Mechanical Behavior of Materials,School of Material Science and Engineering,Xi'an Jiaotong University,Xi'an 710049,China;Shaanxi Key Laboratory of biomedical metallic materials,Northwest Institute for Non-ferrous Metal Research,Xi'an 710016,China;Orthopedics Oncology Institute of Chinese PLA,Tangdu Hospital,Air Force Medical University,Xi'an 710038,China;Shanghai Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Centre for Advanced Materials Processing and Manufacturing(AMPAM),The University of Queensland,St Lucia,QLD 4072,Australia
文献出处：
引用格式：
[1]Sen Yu;Zhe Yu;Dagang Guo;Hui Zhu;Minghua Zhang;Jianye Han;Zhentao Yu;Yemin Cao;Gui Wang-.Enhanced bioactivity and interfacial bonding strength of Ti3Zr2Sn3Mo25Nb alloy through graded porosity and surface bioactivation)[J].材料科学技术（英文版）,2022(05):137-149
A类：
Ti3Zr2Sn3Mo25Nb,bioactivation
B类：
Enhanced,bioactivity,interfacial,bonding,strength,through,graded,porosity,surface,gradient,TLM,rods,were,fabricated,sintering,alloyed,powder,solid,core,sample,was,then,modified,by,Micro,Arc,Oxidation,MAO,electrolyte,containing,calcium,phosphate,hydrothermal,treatment,enabled,secondary,microporous,hydroxyapatite,HA,further,bone,morphogenetic,protein,BMP,loading,immersion,freeze,drying,orderly,nano,particles,evenly,distributed,coatings,result,osteoblasts,could,adhere,grow,well,high,cell,adhesion,rate,functional,situ,shear,testing,indicated,that,had,been,enhanced,significantly,Improvement,formation,osseointegration,titanium,implant,attributed,creased,area,attach,creating,voids,activating,introducing,bioactive,ingredients,such
AB值：
0.613618
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