典型文献
Bacterial MerR family transcription regulators:activation by distortion
文献摘要：
Transcription factors(TFs)modulate gene expression by regulating the accessibility of promoter DNA to RNA polymerases(RNAPs)in bacteria.The MerR family TFs are a large class of bacterial proteins unique in their physiological functions and molecular action:they function as transcription repressors under normal circum-stances,but rapidly transform to transcription activators under various cellular triggers,including oxidative stress,imbalance of cellular metal ions,and antibiotic challenge.The promoters regulated by MerR TFs typically contain an abnormal long spacer between the-35 and-10 elements,where MerR TFs bind and regulate transcription activity through unique mechanisms.In this review,we summarize the function,ligand reception,DNA recognition,and molecular mechanism of transcription regulation of MerR-family TFs.
文献关键词：
中图分类号：
作者姓名：
Chengli Fang;Yu Zhang
作者机构：
Key Laboratory of Synthetic Biology,CAS Center for Excellence in Molecular Plant Sciences,Shanghai Institute of Plant Physiology and Ecology,Chinese Academy of Sciences,Shanghai 200032,China;University of Chinese Academy of Sciences,Beijing 100049,China
文献出处：
引用格式：
[1]Chengli Fang;Yu Zhang-.Bacterial MerR family transcription regulators:activation by distortion)[J].生物化学与生物物理学报（英文版）,2022(01):25-36
A类：
MerR,RNAPs
B类：
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AB值：
0.598503
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
