典型文献
Aptamers as Recognition Elements for Electrochemical Detection of Exosomes
文献摘要：
Exosome analysis is emerging as an attractive noninvasive approach for disease diagnosis and treatment monitoring in the field of liquid biopsy.Aptamer is considered as a promising molecular probe for exosomes detection because of the high binding affinity,remarkable specificity,and low cost.Recently,many approaches have been developed to further improve the performance of electrochemical aptamer based(E-AB)sensors with a lower limit of detection.In this review,we focus on the development of using aptamer as a specific recognition element for exosomes detection in electrochemical sensors.We first introduce recent advances in evolving aptamers against exosomes.Then,we review methods of immobilization aptamers on electrode surfaces,followed by a summary of the main strategies of signal amplification.Finally,we present the insights of the challenges and future directions of E-AB sensors for exosomes analysis.
文献关键词：
中图分类号：
作者姓名：
CHANG Kaili;SUN Peng;DONG Xin;ZHU Chunnan;LIU Xiaojun;ZHENG Dongyun;LIU Chao
作者机构：
Key Laboratory of Cognitive Science of State Ethnic Affairs Commission,Hubei Key Laboratory of Medical Information Analysis and Tumor Diagnosis and Treatment,College of Biomedical Engineering,South-Central Minzu University,Wuhan 430074,P.R.China
文献出处：
引用格式：
[1]CHANG Kaili;SUN Peng;DONG Xin;ZHU Chunnan;LIU Xiaojun;ZHENG Dongyun;LIU Chao-.Aptamers as Recognition Elements for Electrochemical Detection of Exosomes)[J].高等学校化学研究（英文版）,2022(04):879-885
A类：
Aptamers
B类：
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AB值：
0.616387
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