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First Pig-to-Live Human Xenotransplant Produces Mixed Results
文献摘要:
On 7 January 2022,a 57-year-old man with terminal heart dis-ease became the first living human to receive a genetically modi-fied pig organ-a heart-transplanted into his chest during a 8 h surgery at the University of Maryland Medical Center in Baltimore,MD,USA(Fig.1)[1].The pig heart,provided by the biotechnology company Revivicor(Blacksburg,VA,USA),had ten gene modifica-tions intended to boost the chances of a successful pig-to-human transplant.The patient,David Bennett Sr.,initially did well,with the transplanted heart functioning and showing no signs of organ rejection.However,his condition began to deteriorate,and he died about two months later.In a webinar on 20 April 2022,transplant surgeon Bartley Griffith said the heart seemed to have been con-taminated with a pig cytomegalovirus which likely infected and killed Bennett[2].
文献关键词:
作者姓名:
Sarah C.P.Williams
作者机构:
文献出处:
引用格式:
[1]Sarah C.P.Williams-.First Pig-to-Live Human Xenotransplant Produces Mixed Results)[J].工程(英文),2022(09):6-8
A类:
Xenotransplant,Produces,Revivicor,Blacksburg,webinar,Bartley
B类:
First,Pig,Live,Human,Mixed,Results,On,January,year,old,terminal,heart,dis,ease,became,first,living,human,receive,genetically,fied,pig,organ,transplanted,into,his,chest,during,surgery,University,Maryland,Medical,Center,Baltimore,MD,USA,Fig,provided,by,biotechnology,company,VA,had,modifica,tions,intended,boost,chances,successful,patient,David,Bennett,Sr,initially,did,well,functioning,showing,signs,rejection,However,condition,began,deteriorate,died,about,two,months,later,In,April,surgeon,Griffith,said,seemed,have,been,taminated,cytomegalovirus,which,likely,infected,killed
AB值:
0.65107
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