典型文献
Complete Genome Analysis of A New Strain of Coxsackievirus A1 Associated with Severe HFMD in Yunnan, China
文献摘要：
Enteroviruses (EVs) belong to the family Picornaviridae and are divided into 15 species:enterovirus A–L and rhinovirus A–C (. picornaviridae.com). EV-C consists of 23 serotypes, including poliovirus 1-3, CVA1, CVA11, CVA13, CVA17, CVA19, CVA20, CVA21, CVA22, CVA24, EV-C95, EV-C96, EV-C99, EV-C102, EV-C104, EV-C105, EV-C109, EV-C113, EV-C116, EV-C117, and EV-C118, which can cause diseases as herpangina, hand, foot and mouth disease, acute hemorrhagic conjunctivitis (AHC), aseptic meningitis, and acute flaccid paralysis (AFP)[1-3]. CVA1 is only rarely detected during EVs monitoring, so the data of this virus is very limited. Up to now, only six strains of CVA1 with whole genome or polyprotein gene sequence have been published. The prototype strain Tompkins was identified from the fecal sample of a patient with paralytic disease in the Coxsackie, USA in 1947 which was pathogenic for lactating mice and hamsters but not for rhesus monkeys. It caused significant damage to the skeletal muscle of experimental animals, but not to the central nervous system[4]; HT-THLH02F/XJ/CHN/2011 strain and KS-ZPH01F/XJ/CHN/2011 strain were isolated from two healthy children's fecal samples in the Xinjiang Uygur autonomous region of China, in 2011. they could elicit cytopathic effects (CPE) in a human rhabdomyosarcoma (RD) cell line[5]; BBD34 strain was identified from a patient with gastrointestinal disease in Bangladesh in 2009[6]; V18A strain was isolated from fecal sample in Venezuela in 2015;ETH_P8/A1_2016 strain was isolated from the excrement of children who participated in a clean water intervention experiment in Ethiopian, in 2016[7].
文献关键词：
中图分类号：
作者姓名：
FENG Chang Zeng;ZHANG Ming;XU Dan Han;Guo Wei;SUN Hao;YANG Zhao Qing;MA Shao Hui
作者机构：
Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, Yunnan, China;Yunnan Key Laboratory of Vaccine Research Development on Severe Infectious Disease, Kunming 650118, Yunnan, China
文献出处：
引用格式：
[1]FENG Chang Zeng;ZHANG Ming;XU Dan Han;Guo Wei;SUN Hao;YANG Zhao Qing;MA Shao Hui-.Complete Genome Analysis of A New Strain of Coxsackievirus A1 Associated with Severe HFMD in Yunnan, China)[J].生物医学与环境科学（英文版）,2022(03):248-253,前插24-前插25
A类：
Enteroviruses,picornaviridae,CVA1,CVA11,CVA13,CVA17,CVA19,CVA20,CVA21,CVA22,CVA24,C99,C102,C109,C113,C116,C117,C118,herpangina,THLH02F,ZPH01F,BBD34,V18A,Venezuela,excrement
B类：
Complete,Genome,Analysis,New,Strain,Coxsackievirus,Associated,Severe,HFMD,Yunnan,China,EVs,belong,family,Picornaviridae,divided,into,species,enterovirus,rhinovirus,consists,serotypes,including,poliovirus,C95,C96,C104,C105,which,diseases,hand,foot,mouth,acute,hemorrhagic,conjunctivitis,AHC,aseptic,meningitis,flaccid,paralysis,AFP,only,rarely,detected,during,monitoring,data,this,very,limited,Up,now,six,strains,whole,genome,polyprotein,gene,sequence,have,been,published,prototype,Tompkins,was,identified,from,fecal,patient,paralytic,USA,pathogenic,lactating,mice,hamsters,but,not,rhesus,monkeys,It,caused,significant,damage,skeletal,muscle,experimental,animals,central,nervous,system,HT,XJ,CHN,KS,were,isolated,two,healthy,children,samples,Xinjiang,Uygur,autonomous,region,they,could,elicit,cytopathic,effects,CPE,human,rhabdomyosarcoma,RD,cell,line,gastrointestinal,Bangladesh,ETH,P8,participated,clean,water,intervention,Ethiopian
AB值：
0.518349
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