典型文献
A Brief Summary of Current Therapeutic Strategies for Spinal Cord Injury
文献摘要:
Spinal cord injury(SCI)is a tremendous disaster in a person's life.It interrupts the brain-body neuronal circuits,resulting in functional deficits.Pathogenesis of SCI is a progressive and comprehensive event.In clinical trials,attempts to promote nerve regeneration and functional recovery after SCI have met with failures.Recently,with the development of transcriptome sequencing and biomaterials,researchers have struggled to explore novel efficient therapeutic treatments for SCI.Here,we summarize the recent pro-gress that has been made in SCI repair based on the lesion microenvironment,neural circuits,and bioma-terial scaffolds.We also propose several important directions for future research,including targeted-microRNA therapy,blood vessel interventions,and multiple treatment combinations.In short,we hope this review will enlighten researchers in the field and pave the way for SCI therapy.
文献关键词:
中图分类号:
作者姓名:
Chun Yao;Xin Tang;Yuqi Cao;Xuhua Wang;Bin Yu
作者机构:
Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education & NMPA Key Laboratory for the Research and Evaluation of Tissue Engineering Technology Products,Co-Innovation Center of Neuroregeneration,Nantong University,Nantong 226001,China;NHC and CAMS Key Laboratory of Medical Neurobiology,MOE Frontier Science Center for Brain Science and Brain-Machine Integration,School of Brain Science and Brain Medicine,Zhejiang University,Hangzhou 310003,China;Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair,Affiliated Hospital of Nantong University,Nantong University,Nantong 226001,China
文献出处:
引用格式:
[1]Chun Yao;Xin Tang;Yuqi Cao;Xuhua Wang;Bin Yu-.A Brief Summary of Current Therapeutic Strategies for Spinal Cord Injury)[J].工程(英文),2022(06):46-52
A类:
bioma
B类:
Brief,Summary,Current,Therapeutic,Strategies,Spinal,Cord,Injury,cord,injury,SCI,tremendous,disaster,person,life,It,interrupts,brain,body,neuronal,circuits,resulting,functional,deficits,Pathogenesis,progressive,comprehensive,event,clinical,trials,attempts,promote,nerve,regeneration,recovery,after,have,met,failures,Recently,development,transcriptome,sequencing,biomaterials,researchers,struggled,explore,novel,efficient,therapeutic,treatments,Here,we,summarize,recent,that,has,been,made,repair,lesion,microenvironment,neural,scaffolds,We,also,propose,several,important,directions,future,including,targeted,microRNA,therapy,blood,vessel,interventions,multiple,combinations,short,hope,this,review,will,enlighten,field,pave,way
AB值:
0.724383
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