典型文献
Extracardiovascular injury complications in Kawasaki disease
文献摘要：
Importance::Patients with Kawasaki disease (KD) experience various extracardiovascular injury complications, which may affect their outcomes.Objective::To investigate the incidence and clinical characteristics of extracardiovascular complications in children with KD.Methods::The clinical data of patients diagnosed with KD in the First Affiliated Hospital of Guangxi Medical University from January 2003 to January 2021 were reviewed. The clinical characteristics and extracardiovascular complications were compared among patients stratified by age, intravenous immunoglobulin (IVIG) therapy responsiveness, and coronary status.Results::A total of 511 patients with KD were included, 357 (69.9%) were aged 1-5 years. Children aged <1 year (21.5%) and boys (70.8%) were more likely to have coronary artery lesions (CALs). The incidence of incomplete KD was lowest in 1-5-year-old patients (19.6%). Involvement of the hematological system gradually decreased with age (<1 year, 51.8%; 1-5 years, 36.7%; >5 years, 29.5%), whereas the involvement of the joints gradually increased with age (<1 year, 2.7%; 1-5 years, 6.2%; >5 years, 20.5%). Nervous system involvement was more common in IVIG non-responders (15.7% [13/83]
vs. 5.4% [23/428],
P = 0.001). However, there were no significant differences in extracardiovascular injury complications between patients with or without CALs.
Interpretation::KD can involve multiple organ injuries as well as cardiovascular complications, and nervous systerm involvement may be more common in patients unresponsive to IVIG.
文献关键词：
Complication;Coronary artery aneurysm;Extracardiovascular;Intravenous immunoglobulin;Kawasaki disease
中图分类号：
作者姓名：
Liu Jie;Huang Yuqin;Qin Suyuan;Su Danyan;Ye Bingbing;Pang Yusheng
作者机构：
Department of Pediatrics, First Affiliated Hospital, Guangxi Medical University, Nanning, China
文献出处：
引用格式：
[1]Liu Jie;Huang Yuqin;Qin Suyuan;Su Danyan;Ye Bingbing;Pang Yusheng-.Extracardiovascular injury complications in Kawasaki disease)[J].儿科学研究（英文）,2022(04):241-249
A类：
Extracardiovascular,extracardiovascular,systerm
B类：
injury,complications,Kawasaki,disease,Importance,Patients,KD,experience,various,which,may,affect,their,outcomes,Objective,To,investigate,incidence,clinical,characteristics,children,Methods,data,patients,diagnosed,First,Affiliated,Hospital,Guangxi,Medical,University,from,January,were,reviewed,compared,among,stratified,by,intravenous,immunoglobulin,IVIG,therapy,responsiveness,coronary,status,Results,total,included,aged,years,Children,boys,more,likely,have,artery,lesions,CALs,incomplete,lowest,old,Involvement,hematological,system,gradually,decreased,whereas,involvement,joints,increased,Nervous,common,responders,However,there,significant,differences,between,without,Interpretation,multiple,organ,injuries,well,nervous,unresponsive,Complication,Coronary,aneurysm,Intravenous
AB值：
0.498905
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