典型文献
"Elimination of Hepatitis by 2030" : Present Realities and Future Projections
文献摘要：
Each year, viral hepatitis and its complications affect millions of patients and cause one-and-a-half million deaths. To deal with this immense public health burden, international organizations have, as part of their sustainable development goals, set up the plan "Elimination of Hepatitis by 2030," which has been ratified by most countries. The plan’s aims include the prevention of different hepatitis viruses and the treatment of existing patients. However, a mid-term analysis revealed that lest novel maneuvers are adopted, some of the plan’s objectives may not be attained. While new infections seem to be contained by vaccines and other public health measures, the persistent reservoir of chronic hepatitis viruses -hepatitis B virus (HBV) and hepatitis C virus (HCV) - may not be properly addressed. Although antiviral therapy against chronic HCV infection is promising, chronic-HBV-infected persons may not be properly handled. There are about 296 million chronic hepatitis B (CHB) patients in the world, and only 10% of them are aware of their infection. Thus, the undetected CHB patients should be found, and a proper approach should be devised to address this issue, especially in developing countries that harbor the main bulk of CHB patients. In addition, there is no finite therapy for CHB patients, and the safety and efficacy of the existing drugs are also questionable. This indicates the need for novel drugs for CHB patients. In light of this, this study aimed to offer measures that could discover the millions of undetected patients and address the need for developing innovative drugs for CHB patients and thus substantiate the "Elimination of Hepatitis by 2030" plan.
文献关键词：
Hepatitis B virus;Elimination of Hepatitis by 2030;Innovative therapy;Prevention
中图分类号：
作者姓名：
Akbar Sheikh Mohammad Fazle;AL-Mahtab Mamun;Khan Sakirul;Yoshida Osamu;Hiasa Yoichi
作者机构：
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime 791-0295, Japan;Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, BSMMU, Dhaka 1000, Bangladesh;Department of Microbiology, Oita University, Oita, Japan
文献出处：
引用格式：
[1]Akbar Sheikh Mohammad Fazle;AL-Mahtab Mamun;Khan Sakirul;Yoshida Osamu;Hiasa Yoichi-."Elimination of Hepatitis by 2030" : Present Realities and Future Projections)[J].感染性疾病和免疫（英文）,2022(01):3-8
A类：
Realities,lest,questionable
B类：
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AB值：
0.526965
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