典型文献
Advances in new antivirals for chronic hepatitis B
文献摘要：
Chronic hepatitis B virus (HBV) infection remains a global health burden. Timely and effective antiviral therapy is beneficial for patients with HBV infection. With existing antiviral drugs, including nucleos(t)ide analogs and interferon-alfa, patients can achieve viral suppression with improved prognosis. However, the rate of hepatitis B surface antigen loss is low. To achieve a functional cure and even complete cure in chronic hepatitis B patients, new antivirals need to be developed. In this review, we summarized the advantages and disadvantages of existing antiviral drugs and focused on new antivirals including direct-acting antiviral drugs and immunotherapeutic approaches.
文献关键词：
Hepatitis B virus;New antivirals;Functional cure;Complete cure
中图分类号：
作者姓名：
Tang Yanhua;Liang Hongyan;Zeng Ge;Shen Sheng;Sun Jian
作者机构：
State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China
文献出处：
引用格式：
[1]Tang Yanhua;Liang Hongyan;Zeng Ge;Shen Sheng;Sun Jian-.Advances in new antivirals for chronic hepatitis B)[J].中华医学杂志（英文版）,2022(05):571-583
A类：
B类：
Advances,new,antivirals,chronic,hepatitis,Chronic,virus,HBV,infection,remains,global,health,burden,Timely,effective,therapy,beneficial,patients,With,existing,drugs,including,nucleos,ide,analogs,interferon,alfa,can,achieve,suppression,improved,prognosis,However,rate,surface,antigen,loss,low,To,functional,cure,even,complete,need,developed,In,this,review,summarized,disadvantages,focused,direct,acting,immunotherapeutic,approaches,Hepatitis,New,Functional,Complete
AB值：
0.583037
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