典型文献
Irreversible Electroporation Ablation for Atrial Fibrillation: Status and Challenges
文献摘要：
Pulsed electric field (PEF) is a novel energy source by which high-voltage electric pulses are used to create irreversible electroporation. PEF is non-thermal and highly tissue-dependent in which specific targeting of the atrial myocardium is achieved and sparing of adjacent tissues is feasible, theoretically increasing the safety of the procedure, which could potentially break the trade-off between effective lesions and collateral damage and substantially improve risk-benefit ratios in atrial fibrillation (AF) ablation. Although recently published trials have shown a clear effect of AF ablation, large-scale clinical trials are lacking. Current clinical evidence has demonstrated significant efficacy in achieving durable pulmonary vein isolation without ablation-related adverse events. However, their putative benefits regarding efficacy, efficiency, and safety remain to be proven in randomized controlled trials.
文献关键词：
Atrial fibrillation;Irreversible electroporation;Ablation
中图分类号：
作者姓名：
Xie Fei;Chen Yonggang;Chen Xinhua;Zhao Zhihong
作者机构：
Key Laboratory of Pulsed Power Translational Medicine of Zhejiang Province, Hangzhou, Zhejiang 310003, China;The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China;Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, China
文献出处：
引用格式：
[1]Xie Fei;Chen Yonggang;Chen Xinhua;Zhao Zhihong-.Irreversible Electroporation Ablation for Atrial Fibrillation: Status and Challenges)[J].心血管病探索（英文）,2022(01):41-50
A类：
Electroporation
B类：
Irreversible,Ablation,Atrial,Fibrillation,Status,Challenges,Pulsed,electric,field,PEF,novel,energy,source,by,which,voltage,pulses,are,used,create,irreversible,electroporation,thermal,highly,dependent,specific,targeting,atrial,myocardium,achieved,sparing,adjacent,tissues,feasible,theoretically,increasing,safety,procedure,could,potentially,break,trade,off,between,effective,lesions,collateral,damage,substantially,improve,risk,ratios,fibrillation,AF,ablation,Although,recently,published,trials,have,shown,clear,large,scale,clinical,lacking,Current,evidence,has,demonstrated,significant,efficacy,achieving,durable,pulmonary,vein,isolation,without,related,adverse,events,However,their,putative,benefits,regarding,efficiency,remain,proven,randomized,controlled
AB值：
0.698872
相似文献
机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
