典型文献
Impact of satellite blood culture on early diagnosis of sepsis
☆
文献摘要：
Background::The aim of this study was to assess whether satellite blood culture (SBC) can improve turnaround times, antibiotic switching, and patient prognosis, relative to laboratory blood culture (LBC).Methods::Patients with sepsis treated in the intensive care units (ICUs) of Henan Provincial People’s Hospital from February 5, 2018 to January 19, 2019 who met the inclusion criteria were recruited to the study and divided into the SBC group and LBC group according to different blood culture methods. Patient demographics, blood culture, antibiotic adjustment, and prognosis data were collected and compared between the two groups.Results::A total of 204 blood culture sets from 52 ICU patients, including 100 from the medical microbiology LBC group and 104 from the SBC group, were analyzed in this study. There was no significant difference in the positive rates between the two groups. Time from specimen collection to incubation was significantly shorter in the SBC group than that in the LBC group (1.65 h
vs. 3.51 h,
z=-4.09,
P<0.001). The median time from specimen collection to notification of blood culture positivity was 24.83 h in the SBC group and 27.83 h in the LBC group. Median times from adjustment of antibiotics according to the first report were 26.05 h and 51.71 h in the SBC and LBC groups, respectively, while those according to the final report were 97.17 h and 111.45 h, respectively. Median ICU lengths of stay were 15.00 days and 17.00 days in the SBC and LBC groups, respectively, and median ICU lengths of stay were 18.00 days and 23.50 days, respectively. Mean hospitalization costs were 157.99 and 186.73 thousand yuan in the SBC and LBC groups, respectively.
Conclusion::SBC can significantly reduce blood culture turnaround times; however, there were no significant differences between the two blood culture methods in initial reporting of positive cultures, time to adjustment of antibiotic therapy, or medical costs, despite a trend toward improvement.
文献关键词：
Blood culture;Sepsis;Intensive care unit;Antibiotic switching;Turnaround time;Gram stain
中图分类号：
作者姓名：
Guo Ziqi;Guo Bo;Wang Shanmei;Zhang Huifeng;Zhang Wenxiao;Qin Bingyu;Shao Huanzhang
作者机构：
Department of Critical Care Medicine, Henan University People’s Hospital, Zhengzhou, Henan 455000, China;Department of Critical Care Medicine, Henan Provincial People’s Hospital, Zhengzhou, Henan 455000, China;Henan Key Laboratory for Critical Care Medicine, Henan Provincial People’s Hospital, Zhengzhou, Henan 455000, China;Department of Critical Care Medicine, Zhengzhou University People’s Hospital, Zhengzhou, Henan 455000, China;Department of Microbiology Laboratory, Henan Provincial People’s Hospital, Zhengzhou, Henan 455000, China
文献出处：
引用格式：
[1]Guo Ziqi;Guo Bo;Wang Shanmei;Zhang Huifeng;Zhang Wenxiao;Qin Bingyu;Shao Huanzhang-.Impact of satellite blood culture on early diagnosis of sepsis
☆)[J].重症医学（英文）,2022(01):56-60
A类：
Turnaround
B类：
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AB值：
0.432708
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