典型文献
Current status and progress in immunotherapy for malignant pleural mesothelioma
文献摘要：
Malignant pleural mesothelioma (MPM) is a rare and aggressive malignant disease. Currently, the platinum doublet of pemetrexed and cisplatin is the standard first-line treatment for unresectable MPM. However, recent promising results of immunotherapy have markedly changed the landscape of MPM treatment. Further, the ongoing innovative therapeutic strategies are expected to expand the range of treatment options; however, several questions remain unanswered. First, establishing predictive biomarkers with high potency is urgently needed to optimize the patient selection process. Second, further exploration of the combination algorithm is expected to unveil more effective and safe regimens. Moreover, other dilemmas, such as the resistance mechanism of immunotherapy and the role of immunotherapy in perioperative settings, still warrant further exploration.
文献关键词：
immunotherapy;mesothelioma;predictive biomarker
中图分类号：
作者姓名：
Sun Boyang;Dong Yiting;Xu Jiachen;Wang Zhijie
作者机构：
State Key Laboratory of Molecular Oncology, Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China
文献出处：
引用格式：
[1]Sun Boyang;Dong Yiting;Xu Jiachen;Wang Zhijie-.Current status and progress in immunotherapy for malignant pleural mesothelioma)[J].慢性疾病与转化医学（英文）,2022(02):91-99
A类：
B类：
status,progress,immunotherapy,malignant,pleural,mesothelioma,Malignant,MPM,rare,aggressive,disease,Currently,platinum,doublet,pemetrexed,cisplatin,standard,first,line,treatment,unresectable,However,recent,promising,results,have,markedly,changed,landscape,Further,ongoing,innovative,therapeutic,strategies,expected,expand,range,options,however,several,questions,remain,unanswered,First,establishing,predictive,biomarkers,high,potency,urgently,needed,optimize,patient,selection,process,Second,further,exploration,combination,algorithm,unveil,more,effective,safe,regimens,Moreover,dilemmas,such,resistance,mechanism,role,perioperative,settings,still,warrant
AB值：
0.674468
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