典型文献
Prevalence and risk factors associated with Japanese encephalitis virus infection in swine population of Assam,India
文献摘要:
Objective: To assess the prevalence of Japanese encephalitis virus (JEV) and associated risk factors in the swine population of Assam. Methods: A total of 432 swine serum and blood samples were collected from Barpeta and Sonitpur districts of Assam and were screened for the presence of JEV antibodies. Information related to risk factors was collected using a self-designed questionnaire from 120 swine-rearing farmers. Linear-mixed models were used for prevalence estimation. Univariate and multivariate regression models were constructed to evaluate the association of demography, season and management practices with JEV positive status. Results: Overall, the JEV infection prevalence was 51.6% at farm and 47.1% at slaughter premises. Phylogenetic analysis of partial sequence of envelope gene of two positive field samples revealed that both isolates belonged to genotype Ⅲ JEV. Isolate 1 shared a common clade with human isolates while isolate 2 belonged to the same clade as that of other JEV swine strain isolated from India. The final multivariate model showed that two factors including monsoon season (Adjusted OR 5.6; 95% CI 2.1-14.9; P<0.001) and water logging in the area near the pig shelter (Adjusted OR 16.9; 95% CI 6.1-47.3; P<0.001) were associated with greater odds of swine being infected with JEV. Conclusions: High prevalence of JEV in swine population of Assam state indicates a significant risk of virus transmission to humans while risk factor study underlines the urgent need for awareness campaigns in the Assam.
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中图分类号:
作者姓名:
Mir Hussain;Himani Dhanze;Deepa Mehta;M.Suman Kumar;Ravi Kumar Gandham;Megha Gupta;AG Barua;K.P Suresh;Balbir B Singh
作者机构:
Division of Veterinary Public Health,ICAR-Indian Veterinary Research Institute,Izatnagar,Bareilly,India;Division of Animal Biotechnology,ICAR-Indian Veterinary Research Institute,Izatnagar,Bareilly,India;Department of Veterinary Public Health,College of Veterinary Science,Assam Agricultural University,Guwahati,Assam,India;ICAR-National Institute of Veterinary Epidemiology and Disease Informatics,Bengaluru,India;Centre for One Health,Guru Angad Dev Veterinary&Animal Sciences University,Punjab,India
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引用格式:
[1]Mir Hussain;Himani Dhanze;Deepa Mehta;M.Suman Kumar;Ravi Kumar Gandham;Megha Gupta;AG Barua;K.P Suresh;Balbir B Singh-.Prevalence and risk factors associated with Japanese encephalitis virus infection in swine population of Assam,India)[J].亚太热带医药杂志(英文版),2022(11):503-510
A类:
Assam,Barpeta,Sonitpur
B类:
Prevalence,risk,factors,associated,Japanese,encephalitis,virus,infection,swine,population,India,Objective,To,assess,prevalence,JEV,Methods,total,serum,blood,samples,were,collected,from,districts,screened,presence,antibodies,Information,related,was,using,self,designed,questionnaire,rearing,farmers,Linear,mixed,models,used,estimation,Univariate,multivariate,regression,constructed,evaluate,association,demography,season,management,practices,positive,status,Results,Overall,slaughter,premises,Phylogenetic,analysis,partial,sequence,envelope,two,field,revealed,that,both,isolates,belonged,genotype,Isolate,shared,common,clade,while,same,other,strain,isolated,final,showed,including,monsoon,Adjusted,water,logging,area,pig,shelter,greater,odds,being,infected,Conclusions,High,state,indicates,significant,transmission,humans,study,underlines,urgent,need,awareness,campaigns
AB值:
0.520602
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