典型文献
Molecular biomarkers for gestational diabetes mellitus and postpartum diabetes
文献摘要：
Gestational diabetes mellitus (GDM) is a growing public health problem worldwide that threatens both maternal and fetal health. Identifying individuals at high risk for GDM and diabetes after GDM is particularly useful for early intervention and prevention of disease progression. In the last decades, a number of studies have used metabolomics, genomics, and proteomic approaches to investigate associations between biomolecules and GDM progression. These studies clearly demonstrate that various biomarkers reflect pathological changes in GDM. The established markers have potential use as screening and diagnostic tools in GDM and in postpartum diabetes research. In the present review, we summarize recent studies of metabolites, single-nucleotide polymorphisms, microRNAs, and proteins associated with GDM and its transition to postpartum diabetes, with a focus on their predictive value in screening and diagnosis.
文献关键词：
Gestational diabetes mellitus;Biomarkers;Metabolomics;Proteomics;microRNA;Single-nucleotide polymorphism
中图分类号：
作者姓名：
Lu Wenqian;Hu Cheng
作者机构：
Shanghai Diabetes Institute, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200233, China;The Third School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong 510630, China;Department of Endocrinology and Metabolism, Fengxian Central Hospital Affiliated to the Southern Medical University, Shanghai 201400, China
文献出处：
引用格式：
[1]Lu Wenqian;Hu Cheng-.Molecular biomarkers for gestational diabetes mellitus and postpartum diabetes)[J].中华医学杂志（英文版）,2022(16):1940-1951
A类：
B类：
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AB值：
0.628606
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