典型文献
Surface Bioactive Modification of Alumina Ceramic by Mineralization in Modified SBF
文献摘要:
In the present study,it is found that the prepared alumina ceramics has better mineralization ability in a newly revised simu-lated body fluid.With the extension of mineralization time,the amount of hydroxyapatite(HA)crystals deposited on the surface of alumina ceramics also increased gradually.The results of cell biological experiments of alumina ceramics with hydroxyapatite surface layer demonstrate that the mineralized materials have better biological activity and osteogenesis properties in vitro.In the meanwhile,the ALP activity and expression of osteogenesis-related genes(OPN,ALP,Col-I,and OCN)of mouse bone marrow stromal stem cells on the samples were significantly promoted by increasing the formation of HA on the surface of alumina ceramics.Our research concluded that alumina ceramics with HA phase on surface had great potential to be developed as a sort of bioactive material in the bone repair field.
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作者姓名:
Wenmin Zhang;Caixia Liang;Qixuan He;Xiaoyan Cao;Fangli Yuan;Jiandong Ye
作者机构:
School of Material Science and Engineering,South China University of Technology,Guangzhou 510640,China;National Engineering Research Center for Tissue Restoration and Reconstruction,Guangzhou 510006,China;Guangdong Fapon Biotech Co.Ltd,Dongguan 523808,China;Inspection and Quarantine Comprehensive Technology Centre of Foshan Entry-exit Inspection and Quarantine Bureau,Foshan 528042,China;Key Laboratory of Biomedical Materials of Ministry of Education,South China University of Technology,Guangzhou 510641,China
文献出处:
引用格式:
[1]Wenmin Zhang;Caixia Liang;Qixuan He;Xiaoyan Cao;Fangli Yuan;Jiandong Ye-.Surface Bioactive Modification of Alumina Ceramic by Mineralization in Modified SBF)[J].仿生工程学报(英文版),2022(06):1637-1644
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0.610187
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