典型文献
Clinical Analysis of Primary Tracheobronchial Tumors in Children and Evaluation of the Predicting Models for Mucoepidermoid Carcinoma
文献摘要：
Objective:To determine the clinical characteristics and prognosis of primary tracheobronchial tumors(PTTs)in children,and to explore the most common tumor identification methods.Methods:The medical records of children with PTTs who were hospitalized at the Children's Hospital of Chongqing Medical University from January 1995 to January 2020 were reviewed retrospectively.The clinical features,imaging,treatments,and outcomes of these patients were statistically analyzed.Machine learning techniques such as Gaussian na?ve Bayes,support vector machine(SVM)and decision tree models were used to identify mucoepidermoid carcinoma(ME).Results:A total of 16 children were hospitalized with PTTs during the study period.This included 5(31.3％)children with ME,3(18.8％)children with inflammatory myofibroblastic tumors(IMT),2 children(12.5％)with sarcomas,2(12.5％)children with papillomatosis and 1 child(6.3％)each with carcinoid carcinoma,adenoid cystic carcinoma(ACC),hemangioma,and schwannoma,respectively.ME was the most common tumor type and amongst the 3 ME recognition methods,the SVM model showed the best performance.The main clinical symptoms of PPTs were cough(81.3％),breathlessness(50％),wheezing(43.8％),progressive dyspnea(37.5％),hemoptysis(37.5％),and fever(25％).Of the 16 patients,7 were treated with surgery,8 underwent bronchoscopic tumor resection,and 1 child died.Of the 11 other children,3 experienced recurrence,and the last 8 remained disease-free.No deaths were observed during the follow-up period.Conclusion:PTT are very rare in children and the highest percentage of cases is due to ME.The SVM model was highly accurate in identifying ME.Chest CT and bronchoscopy can effectively diagnose PTTs.Surgery and bronchoscopic intervention can both achieve good clinical results and the prognosis of the 11 children that were followed up was good.
文献关键词：
中图分类号：
作者姓名：
Chen ZHANG;Wen-long FU;Ji-hong DAI;Yong-gang LI;Xing-ye TANG;Xiao-feng MA;Gang GENG;Ying LI;Ting YANG;Li YAN;Jing-yue LIU;Zheng LIU;Xiao-ping YUAN;Dai-yin TIAN
作者机构：
Department of Pulmonology,Children s Hospital of Chongqing Medical University,Chongqing 400014,China;Department of Pediatrics,Chongqing Fifth People's Hospital,Chongqing 400014,China
文献出处：
引用格式：
[1]Chen ZHANG;Wen-long FU;Ji-hong DAI;Yong-gang LI;Xing-ye TANG;Xiao-feng MA;Gang GENG;Ying LI;Ting YANG;Li YAN;Jing-yue LIU;Zheng LIU;Xiao-ping YUAN;Dai-yin TIAN-.Clinical Analysis of Primary Tracheobronchial Tumors in Children and Evaluation of the Predicting Models for Mucoepidermoid Carcinoma)[J].当代医学科学(英文),2022(04):778-784
A类：
Tracheobronchial,Mucoepidermoid,PTTs,carcinoid,breathlessness,bronchoscopic
B类：
Clinical,Analysis,Primary,Tumors,Children,Evaluation,Predicting,Models,Carcinoma,Objective,To,determine,clinical,characteristics,prognosis,primary,tracheobronchial,tumors,children,explore,most,common,identification,methods,Methods,medical,records,who,were,hospitalized,Hospital,Chongqing,Medical,University,from,January,reviewed,retrospectively,features,imaging,treatments,outcomes,these,patients,statistically,analyzed,Machine,learning,techniques,such,Gaussian,Bayes,support,vector,machine,decision,tree,models,used,mucoepidermoid,carcinoma,ME,Results,total,during,study,period,This,included,inflammatory,myofibroblastic,IMT,sarcomas,papillomatosis,each,adenoid,cystic,ACC,hemangioma,schwannoma,respectively,was,type,amongst,recognition,showed,best,performance,symptoms,PPTs,cough,wheezing,progressive,dyspnea,hemoptysis,fever,Of,treated,surgery,underwent,resection,died,other,experienced,recurrence,remained,disease,free,No,deaths,observed,Conclusion,very,rare,highest,percentage,cases,due,highly,accurate,identifying,Chest,bronchoscopy,can,effectively,diagnose,Surgery,intervention,both,achieve,good,results,that,followed
AB值：
0.563096
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