典型文献
Non-invasive gene delivery across the blood-brain barrier: present and future perspectives
文献摘要:
The aging of society has arrived, and is accompanied by an increase in the absolute numbers of patients with neurological disorders, such as Alzheimer's and Parkinson's diseases (Feigin et al., 2020). Such diseases, particularly Alzheimer's disease and other forms of dementia, affect not only the patients themselves, but also the people around them, including family members and care givers. As a result, such neurological disorders are thought to carry a larger social burden compared to other diseases. The most critical point in the current situation is that there is no effective treatment despite the fact that the number of patients increase with the aging of the population. Gene therapy has great promise for the treatment of neurological disorders (Sun and Roy, 2021), but delivering therapeutic genes is a major impediment for the success of gene therapy.
文献关键词:
中图分类号:
作者姓名:
Seigo Kimura
作者机构:
Laboratory for Molecular Design of Pharmaceutics,Faculty of Pharmaceutical Sciences,Hokkaido University,Sapporo,Japan;Laboratory of Innovative Nanomedicine,Faculty of Pharmaceutical Sciences,Hokkaido University,Sapporo,Japan
文献出处:
引用格式:
[1]Seigo Kimura-.Non-invasive gene delivery across the blood-brain barrier: present and future perspectives)[J].中国神经再生研究(英文版),2022(04):785-787
A类:
Feigin,givers
B类:
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AB值:
0.60067
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