典型文献
Index of microcirculatory resistance:state-of-the-art and potential applications in computational simulation of coronary artery disease
文献摘要：
The dysfunction of coronary microcirculation is an important cause of coronary artery disease (CAD). The index of microcirculatory resistance (IMR) is a quantitative evaluation of coronary microcirculatory function, which provides a significant reference for the prediction, diagnosis, treatment, and prognosis of CAD. IMR also plays a key role in investigating the interaction between epicardial and microcirculatory dysfunctions, and is closely associated with coronary hemodynamic parameters such as flow rate, distal coronary pressure, and aortic pressure, which have been widely applied in computational studies of CAD. However, there is currently a lack of consensus across studies on the normal and pathological ranges of IMR. The relationships between IMR and coronary hemodynamic parameters have not been accurately quantified, which limits the application of IMR in computational CAD studies. In this paper, we discuss the research gaps between IMR and its potential applications in the computational simulation of CAD. Computational simulation based on the combination of IMR and other hemodynamic parameters is a promising technology to improve the diagnosis and guide clinical trials of CAD.
文献关键词：
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作者姓名：
Yingyi GENG;Xintong WU;Haipeng LIU;Dingchang ZHENG;Ling XIA
作者机构：
Key Laboratory for Biomedical Engineering of Ministry of Education,Institute of Biomedical Engineering,Zhejiang University,Hangzhou310027,China;Research Centre of Intelligent Healthcare,Faculty of Health and Life Science,Coventry University,Coventry CV15FB,UK
引用格式：
[1]Yingyi GENG;Xintong WU;Haipeng LIU;Dingchang ZHENG;Ling XIA-.Index of microcirculatory resistance:state-of-the-art and potential applications in computational simulation of coronary artery disease)[J].浙江大学学报（英文版）（B辑：生物医学和生物技术）,2022(02):123-140
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AB值：
0.491514
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