典型文献
Formation of the Looming-evoked Innate Defensive Response during Postnatal Development in Mice
文献摘要:
Environmental threats often trigger innate defen-sive responses in mammals.However,the gradual devel-opment of functional properties of these responses during the postnatal development stage remains unclear.Here,we report that looming stimulation in mice evoked flight behavior commencing at P14-16 and had fully developed by P20-24.The visual-evoked innate defensive response was not significantly altered by sensory deprivation at an early postnatal stage.Furthermore,the percentages of wide-field and horizontal cells in the superior colliculus were notably elevated at P20-24.Our findings define a developmental time window for the formation of the visual innate defense response during the early postnatal period and provide important insight into the underlying mechanism.
文献关键词:
中图分类号:
作者姓名:
Shanping Chen;Huiying Tan;Zhijie Wang;Yu-ting Tseng;Xiaotao Li;Liping Wang
作者机构:
Shenzhen Key Lab of Neuropsychiatric Modulation,Guang-dong Provincial Key Laboratory of Brain Connectome and Behavior,CAS Key Laboratory of Brain Connectome and Manipulation,the Brain Cognition and Brain Disease Insti-tute,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen-Hong Kong Institute of Brain Science-ShenzhenFundamental Research Institutions,Shenzhen 518055,China;University of Chinese Academy of Sciences,Beijing 100049,China;Department of Brain and Cognitive Sciences,McGovern Institute for Brain Research,Massachusetts Institute of Technology,Cambridge,MA 02139,USA
文献出处:
引用格式:
[1]Shanping Chen;Huiying Tan;Zhijie Wang;Yu-ting Tseng;Xiaotao Li;Liping Wang-.Formation of the Looming-evoked Innate Defensive Response during Postnatal Development in Mice)[J].神经科学通报(英文版),2022(07):741-752
A类:
Looming,defen,commencing,colliculus
B类:
Formation,evoked,Innate,Defensive,Response,during,Postnatal,Development,Mice,Environmental,threats,often,trigger,innate,responses,mammals,However,gradual,functional,properties,these,postnatal,stage,remains,unclear,Here,report,that,looming,stimulation,mice,flight,behavior,P14,had,fully,developed,by,P20,visual,defensive,was,significantly,altered,sensory,deprivation,early,Furthermore,percentages,wide,field,horizontal,cells,superior,were,notably,elevated,Our,findings,define,developmental,window,formation,defense,period,provide,important,insight,into,underlying,mechanism
AB值:
0.628408
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