典型文献
Biosensor-based assay of exosome biomarker for early diagnosis of cancer
文献摘要：
Cancer imposes a severe threat to people's health and lives,thus pressing a huge medical and economic burden on individuals and communities.Therefore,early diagnosis of cancer is indispensable in the timely prevention and effective treatment for patients.Exosome has recently become an attractive cancer biomarker in noninvasive early diagnosis because of the unique physiology and pathology functions,which reflects remarkable information regarding the cancer microenvironment,and plays an important role in the occurrence and evolution of cancer.Meanwhile,biosensors have gained great attention for the detection of exosomes due to their superior properties,such as convenient operation,real-time readout,high sensitivity,and remarkable specificity,suggesting promising biomedical applications in the early diagnosis of cancer.In this review,the latest advances of biosensors regarding the assay of exosomes were summarized,and the superiorities of exosomes as markers for the early diagnosis of cancer were evaluated.Moreover,the recent challenges and further opportunities of developing effective biosensors for the early diagnosis of cancer were discussed.
文献关键词：
中图分类号：
作者姓名：
Ying Deng;Zhaowei Sun;Lei Wang;Minghui Wang;Jie Yang;Genxi Li
作者机构：
State Key Laboratory of Pharmaceutical Biotechnology,School of Life Sciences,Nanjing University,Nanjing 210023,China
文献出处：
引用格式：
[1]Ying Deng;Zhaowei Sun;Lei Wang;Minghui Wang;Jie Yang;Genxi Li-.Biosensor-based assay of exosome biomarker for early diagnosis of cancer)[J].医学前沿,2022(02):157-175
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B类：
Biosensor,assay,biomarker,early,diagnosis,cancer,Cancer,imposes,severe,threat,people,health,lives,thus,pressing,huge,economic,burden,individuals,communities,Therefore,indispensable,timely,prevention,effective,treatment,patients,Exosome,has,recently,become,attractive,noninvasive,because,unique,physiology,pathology,functions,which,reflects,remarkable,information,regarding,microenvironment,plays,important,role,occurrence,evolution,Meanwhile,biosensors,have,gained,great,attention,detection,exosomes,due,their,properties,such,convenient,operation,real,readout,high,sensitivity,specificity,suggesting,promising,biomedical,applications,In,this,review,latest,advances,were,summarized,superiorities,markers,evaluated,Moreover,challenges,further,opportunities,developing,discussed
AB值：
0.618378
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