典型文献
A novel inhibitor of the jasmonic acid signaling pathway represses herbivore resistance in tea plants
文献摘要：
The jasmonic acid(JA)signaling pathway plays a vital role in mediating plant resistance to herbivores.The tea plant(Camellia sinensis)is one of the most important woody cash crops in the world.Due to the lack of genetic transformation systems for tea plants,how the JA signaling pathway works in tea plants has not yet been determined.Now,with the development of cross-disciplines,chemical biology provides new means for analyzing the JA signaling pathway.In the present study,the structure of the small-molecule isoquinoline compound ZINC71820901(lyn3)was obtained from the ZINC molecular library through virtual screening based on the structure of the crystal COI1-JAZ1 co-receptor and was found to act as an inhibitor of the JA signaling pathway in both Arabidopsis and tea plants.Our results revealed that lyn3 repressed tea plant resistance to Ectropis grisescens mainly by decreasing the accumulation of(-)-epicatechin and(-)-epigallocatechin via repression of the JA signaling pathway,which functioned in a modulation manner different from that of the already known inhibitor salicylhydroxamic acid(SHAM).As a novel inhibitor of the JA signaling pathway,lyn3 provides a specific option for further research on the JA pathway.
文献关键词：
中图分类号：
作者姓名：
Songbo Lin;Meng Ye;Xiwang Li;Yuxian Xing;Miaomiao Liu;Jin Zhang;Xiaoling Sun
作者机构：
Tea Research Institute,Chinese Academy of Agricultural Sciences,No.9 South Meiling Road,Hangzhou 310008,Zhejiang,China;Key Laboratory of Tea Biology and Resources Utilization,Ministry of Agriculture and Rural Affairs,No.9 South Meiling Road,Hangzhou 310008,Zhejiang,China
文献出处：
引用格式：
[1]Songbo Lin;Meng Ye;Xiwang Li;Yuxian Xing;Miaomiao Liu;Jin Zhang;Xiaoling Sun-.A novel inhibitor of the jasmonic acid signaling pathway represses herbivore resistance in tea plants)[J].园艺研究（英文）,2022(01):96-105
A类：
ZINC71820901,lyn3,salicylhydroxamic
B类：
novel,inhibitor,jasmonic,acid,signaling,pathway,represses,resistance,tea,plants,plays,vital,role,mediating,herbivores,Camellia,sinensis,most,important,woody,cash,crops,world,Due,lack,genetic,transformation,systems,how,works,has,not,yet,been,determined,Now,development,cross,disciplines,chemical,biology,provides,new,means,analyzing,In,present,study,structure,small,molecule,isoquinoline,compound,was,obtained,from,molecular,library,through,virtual,screening,crystal,COI1,JAZ1,receptor,found,act,both,Arabidopsis,Our,results,revealed,that,repressed,Ectropis,grisescens,mainly,by,decreasing,accumulation,epicatechin,epigallocatechin,via,repression,which,functioned,modulation,manner,different,already,known,SHAM,specific,option,further,research
AB值：
0.535362
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机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
