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典型文献
Polarization microwave-induced thermoacoustic imaging for quantitative characterization of deep biological tissue microstructures
文献摘要:
Polarization optical imaging can be used to characterize anisotropy in biological tissue microstructures and has been demonstrated to be a powerful tool for clinical diagnosis.However,the approach is limited by an inability to image targets deeper than~1 mm due to strong optical scattering in biological tissues.As such,we propose a novel polarization microwave-induced thermoacoustic imaging(P-MTAI)technique to noninvasively detect variations in deep tissue by exploiting the thermoacoustic signals induced by four pulsed microwaves of varying polarization orientations.The proposed P-MTAI method overcomes the penetration limits of conventional polarization optical imaging and provides submillimeter resolution over depths of several centimeters.As part of the paper,the structural characteristics of tissues were quantified using a new parameter,the degree of micro-wave absorption anisotropy.P-MTAI was also applied to the noninvasive detection of morphological changes in cardiomyocytes as they transitioned from ordered to disordered states,providing a potential indication of myocardial infarction.
文献关键词:
作者姓名:
YUJING LI;SHANXIANG ZHANG;LINGHUA WU;ZHONGWEN CHENG;ZHENHUI ZHANG;HAOHAO WANG;SHUXIANG ZHAO;MINGYANG REN;SIHUA YANG;DA XING;HUAN QIN
作者机构:
MOE Key Laboratory of Laser Life Science&Institute of Laser Life Science,College of Biophotonics,South China Normal University,Guangzhou 510631,China;Guangdong Provincial Key Laboratory of Laser Life Science,College of Biophotonics,South China Normal University,Guangzhou 510631,China;Guangzhou Key Laboratory of Spectral Analysis and Functional Probes,College of Biophotonics,South China Normal University,Guangzhou 510631,China
引用格式:
[1]YUJING LI;SHANXIANG ZHANG;LINGHUA WU;ZHONGWEN CHENG;ZHENHUI ZHANG;HAOHAO WANG;SHUXIANG ZHAO;MINGYANG REN;SIHUA YANG;DA XING;HUAN QIN-.Polarization microwave-induced thermoacoustic imaging for quantitative characterization of deep biological tissue microstructures)[J].光子学研究(英文),2022(05):1297-1306
A类:
MTAI
B类:
Polarization,induced,thermoacoustic,imaging,quantitative,characterization,biological,microstructures,optical,can,used,characterize,anisotropy,has,been,demonstrated,powerful,tool,clinical,diagnosis,However,approach,limited,by,inability,image,targets,deeper,than,due,strong,scattering,tissues,such,novel,polarization,technique,noninvasively,variations,exploiting,signals,four,pulsed,microwaves,varying,orientations,proposed,method,overcomes,penetration,limits,conventional,provides,submillimeter,resolution,depths,several,centimeters,part,paper,structural,characteristics,were,quantified,using,new,parameter,degree,absorption,was,also,applied,detection,morphological,changes,cardiomyocytes,they,transitioned,from,disordered,states,providing,potential,indication,myocardial,infarction
AB值:
0.599063
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