典型文献
Fabrication of Mesoporous SiO2@CaSiO3 Hollow Spheres as Carriers for pH-sensitive Drug Delivery
文献摘要:
Hollow mesoporous silica(HM-SiO2)was prepared by the improved stober method.On this basis,HM-SiO2 was dispersed in an alkaline solution for surface etching.Meanwhile,calcium source was introduced to combine with SiO32-on the surface to form a CaSiO3 shell layer and an unprecedent SiO2@CaSiO3 sphere with a hollow double-shell structure was obtained.The as-synthesized SiO2@CaSiO3 was characterized by X-ray diffraction(XRD),scanning electron microscopy(SEM),transmission electron microscopy(TEM),N2-BET,IR and UV-Vis techniques,and its sustained release capacity of doxorubicin(DOX)loading was investigated.The drug loading capacity can be achieved to 0.692 mg DOX/mg SiO2@CaSiO3,exhibiting pH-responsivity under low pH conditions.
文献关键词:
中图分类号:
作者姓名:
YUAN Mingwei;SHI Shunli;LUO Yanping;YU Ying;WANG Shuhua;CHEN Chao
作者机构:
Key Laboratory of Jiangxi Province for Environment and Energy Catalysis,College of Chemistry,Nanchang University,Nanchang 330031,P.R.China
文献出处:
引用格式:
[1]YUAN Mingwei;SHI Shunli;LUO Yanping;YU Ying;WANG Shuhua;CHEN Chao-.Fabrication of Mesoporous SiO2@CaSiO3 Hollow Spheres as Carriers for pH-sensitive Drug Delivery)[J].高等学校化学研究(英文版),2022(04):999-1004
A类:
stober
B类:
Fabrication,Mesoporous,SiO2,CaSiO3,Hollow,Spheres,Carriers,sensitive,Drug,Delivery,mesoporous,silica,HM,was,prepared,by,improved,method,On,this,basis,dispersed,alkaline,solution,surface,etching,Meanwhile,calcium,source,introduced,combine,SiO32,form,shell,layer,unprecedent,sphere,hollow,double,structure,obtained,synthesized,characterized,ray,diffraction,scanning,electron,microscopy,transmission,TEM,N2,BET,UV,Vis,techniques,its,sustained,release,capacity,doxorubicin,DOX,loading,investigated,drug,achieved,exhibiting,responsivity,under,conditions
AB值:
0.627127
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