典型文献
Application of Percutaneous Endoscopic Gastrojejunostomy in Duodenal Crohn's Disease-Associated Strictures
文献摘要：
Background Duodenal Crohn's disease(CD)-associated strictures are related to a high risk of malnutrition,and effective methods of enteral nutrition(EN)are needed to support these patients.The purpose of this study was to evaluate the efficacy and safety of percutaneous endoscopic gastrojejunostomy(PEG-J)for the treatment of duodenal CD-associated strictures.Methods Patients with strictures associated with duodenal CD were recruited.The clinical data,stricture characteristics,nutritional status,duration of PEG-J tube placement,complications,and follow-up periods were recorded.Results A total of 24 patients with duodenal CD-associated strictures underwent PEG-J tube placement.The PEG-J tubes were successfully placed in 100％of the patients within an average of 19.04±2.94 minutes.There were no procedure-related complications.There were no major complications after PEG-J tube placement,and only two minor complications(8.33％)occurred.PEG-J was well tolerated in all patients.The mean Karnofsky score was 67.50±7.94 points and 83.33±7.02 points(P=0.000),the mean body mass index was 17.02±1.85 kg/m2 and 18.10±1.78 kg/m2(P=0.045),and the mean Alb level was 35.28±5.35 g/dl and 38.68±5.10 g/dl(P=0.029)before PEG-J and 3 months after PEG-J,respectively.The median CD Activity Index(CDAI score)was 144(range 87-280)and the median C-reactive protein(CRP)was 1.90 mg/L(0.5-67.9 mg/L)after PEG-J,which were significantly lower than the respective 196 mg/L(range 114-331 mg/L)(P=0.044)and 3.75 mg/L(range 0.5-67 mg/L)(P=0.033)before PEG-J.Conclusion PEG-J was a safe,well-tolerated and effective method for the treatment of duodenal CD-associated strictures.PEG-J improved the patient's nutritional status and reduced disease CD activity.These findings suggest that PEG-J is an option for EN in patients with duodenal CD-associated strictures.
文献关键词：
中图分类号：
作者姓名：
Juan Juan Zhang;Ying Dong Xie;Tian Tian Liu;Bin Lin Da;Yan Qing Diao;Yi Li;Zhi Ming Wang
作者机构：
Department of General Surgery,Affiliated Jinling Hospital,Medical School of Nanjing University,Nanjing,Jiangsu 210002,China;Ultrasonography Department,Affiliated Jinling Hospital,Medical School of Nanjing University,Nanjing,Jiangsu 210002,China
文献出处：
引用格式：
[1]Juan Juan Zhang;Ying Dong Xie;Tian Tian Liu;Bin Lin Da;Yan Qing Diao;Yi Li;Zhi Ming Wang-.Application of Percutaneous Endoscopic Gastrojejunostomy in Duodenal Crohn's Disease-Associated Strictures)[J].肿瘤营养学杂志（英文）,2022(04):199-203
A类：
Gastrojejunostomy,Duodenal,Strictures,strictures,gastrojejunostomy
B类：
Application,Percutaneous,Endoscopic,Crohn,Disease,Associated,Background,disease,associated,are,related,high,risk,malnutrition,effective,methods,enteral,EN,needed,support,these,patients,purpose,this,study,was,evaluate,efficacy,safety,percutaneous,endoscopic,PEG,treatment,duodenal,Methods,Patients,were,recruited,clinical,data,characteristics,nutritional,status,duration,placement,complications,follow,periods,recorded,Results,total,underwent,tubes,successfully,placed,within,average,minutes,There,procedure,major,after,only,two,minor,occurred,well,tolerated,all,mean,Karnofsky,score,points,body,mass,Alb,level,dl,before,months,respectively,median,Activity,Index,CDAI,range,reactive,protein,which,significantly,lower,than,Conclusion,improved,reduced,activity,These,findings,suggest,that,option
AB值：
0.429508
相似文献
机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
