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典型文献
Engineered Production of Bioactive Natural Products from Medicinal Plants
文献摘要:
Plant natural products have been particularly important due to their use in food,cosmetic,and pharmaceutical industries.In particular,Traditional Chinese Medicine provides a precious potential for the discovery of bioactive natural products and development of novel modern medicines.However,the existing production methods for plant natural products such as chemical synthesis and plant extraction does not meet the current demand.Due to their environmental and economic concerns,engineered production of valuable natural products in microbial hosts has become an attractive alternative platform.This review covers the recent advances in the engineered production of plant natural products in microorganisms.A special focus was placed on the biotechnological production of plant-derived terpenoids,flavonoids,and alkaloids.Some successful examples of engineered production of plant natural products(or their precursors)such as artemisinin,paclitaxel,naringenin,quercetin,berberine,and noscapine are summarized.This clearly indicates that the engineered production method is a promising approach with various advantages over current methods.
文献关键词:
作者姓名:
Ozkan Fidan;Jie Ren;Jixun Zhan
作者机构:
Department of Bioengineering,Faculty of Life and Natural Sciences,Abdullah Gül University,Kayseri,Turkey;Department of Biological Engineering,College of Engineering,Utah State University,Logan,Utah,USA
引用格式:
[1]Ozkan Fidan;Jie Ren;Jixun Zhan-.Engineered Production of Bioactive Natural Products from Medicinal Plants)[J].世界中医药杂志(英文版),2022(01):59-76
A类:
noscapine
B类:
Engineered,Production,Bioactive,Natural,Products,from,Medicinal,Plants,natural,products,have,been,particularly,important,due,their,use,food,cosmetic,pharmaceutical,industries,In,Traditional,Chinese,Medicine,provides,precious,potential,discovery,bioactive,development,novel,modern,medicines,However,existing,production,methods,plant,such,chemical,synthesis,extraction,does,not,meet,current,demand,Due,environmental,economic,concerns,engineered,valuable,microbial,hosts,has,become,attractive,alternative,platform,This,review,covers,recent,advances,microorganisms,special,focus,was,placed,biotechnological,derived,terpenoids,flavonoids,alkaloids,Some,successful,examples,precursors,artemisinin,paclitaxel,naringenin,quercetin,berberine,are,summarized,clearly,indicates,that,promising,approach,various,advantages
AB值:
0.671192
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