典型文献
Integration strategy of network pharmacology in Traditional Chinese Medicine:a narrative review
文献摘要：
Traditional Chinese Medicine(TCM)has been extensively used as a mainstay for treating various pathologies.Combing the pharmacology and systems biology approaches,the network pharmacology(NP)approach was developed to predict the probable mechanism underlying the therapeutic effect of TCM.However,approaches solely based on NP cannot effectively elucidate the curative mechanism in a holistic and reliable manner due to limitations in NP-based methods and complexity of TCM components.Thus,integration strategies combining NP with other approaches are increasingly being used.Since the interdisciplinary research in TCM has received much attention in the advent of the big data era of which the NP-based integration strategy is broadly used,the strategy is clearly elaborated in the present review.We summarized several NP-based integration strategies and their applications in TCM studies,including multi-omics approach,gut microbiota study,chemical information analysis,data-mining,and network toxicology study.
文献关键词：
中图分类号：
作者姓名：
WU Jiashuo;ZHANG Fangqing;LI Zhuangzhuang;JIN Weiyi;SHI Yue
作者机构：
Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100193,China;Hebei Medical University,Shijiazhuang 050017,China
文献出处：
引用格式：
[1]WU Jiashuo;ZHANG Fangqing;LI Zhuangzhuang;JIN Weiyi;SHI Yue-.Integration strategy of network pharmacology in Traditional Chinese Medicine:a narrative review)[J].中医杂志（英文版）,2022(03):479-486
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Integration,strategy,network,pharmacology,Traditional,Chinese,Medicine,narrative,review,TCM,has,been,extensively,used,mainstay,treating,various,pathologies,Combing,systems,biology,approaches,NP,was,developed,predict,probable,mechanism,underlying,therapeutic,However,solely,cannot,effectively,elucidate,curative,holistic,reliable,manner,due,limitations,methods,complexity,components,Thus,integration,strategies,combining,other,are,increasingly,being,Since,interdisciplinary,research,received,much,attention,advent,big,data,which,broadly,clearly,elaborated,present,We,summarized,several,their,applications,studies,including,multi,omics,gut,microbiota,study,chemical,information,analysis,mining,toxicology
AB值：
0.628347
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