典型文献
Independent temporal lobe epilepsy in patients with tuberous sclerosis complex
文献摘要：
Tuberous sclerosis complex (TSC) is a rare disease that involves multiple organs, including the brain; approximately 80%-90% of TSC patients exhibit TSC-associated epilepsy. Independent temporal lobe epilepsy (TLE), TSC-unrelated epilepsy, is particularly rare in patients with TSC. Here, we describe three patients with TSC with independent TLEs that were confirmed by stereo-electroencephalography (EEG), postoperative pathological findings, and seizure outcome at follow-up. The patients were retrospectively enrolled at two centers; their ictal epileptiform discharge onsets were determined using electrode contacts in the hippocampus during stereo-EEG. The three patients underwent anterior temporal lobectomies and remained seizure-free at 1-5 years after surgery. Postoperative pathological examinations confirmed hippocampal sclerosis in all three patients. Furthermore, postoperative intelligence quotient improvement was evident in one patient, while the quality of life was improved in two patients at 12 months after surgery.
文献关键词：
Anterior temporal lobectomy;Hippocampal sclerosis;Temporal lobe epilepsy;Tuberous sclerosis complex
中图分类号：
作者姓名：
Liu Tinghong;Ding Jing;Zhang Shaohui;Wang Yangshuo;Xu Jinshan;Yuan Liu;Zhai Feng;Zhang Guojun;Liang Shuli
作者机构：
Department of Functional Neurosurgery, Key Laboratory of Major Disease in Children, Ministry of Education, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, China;Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai, China;Department of Neurosurgery, Fourth Medical Center, PLA General Hospital, Beijing, China
文献出处：
引用格式：
[1]Liu Tinghong;Ding Jing;Zhang Shaohui;Wang Yangshuo;Xu Jinshan;Yuan Liu;Zhai Feng;Zhang Guojun;Liang Shuli-.Independent temporal lobe epilepsy in patients with tuberous sclerosis complex)[J].儿科学研究（英文）,2022(01):23-28
A类：
Tuberous,TLEs,ictal,epileptiform,lobectomies
B类：
Independent,temporal,epilepsy,patients,tuberous,sclerosis,complex,TSC,rare,disease,that,involves,multiple,organs,including,brain,approximately,exhibit,associated,unrelated,particularly,Here,describe,three,independent,were,confirmed,by,stereo,electroencephalography,EEG,postoperative,pathological,findings,seizure,outcome,follow,up,retrospectively,enrolled,two,centers,their,discharge,onsets,determined,using,electrode,contacts,hippocampus,during,underwent,anterior,remained,free,years,after,surgery,Postoperative,examinations,hippocampal,all,Furthermore,intelligence,quotient,improvement,was,evident,one,while,quality,life,improved,months,Anterior,lobectomy,Hippocampal,Temporal
AB值：
0.514541
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