典型文献
How much underfeeding can the critically ill adult patient tolerate?
文献摘要：
Critical illness leads to significant metabolic alterations that should be considered when providing nutritional support. Findings from key randomized controlled trials (RCTs) indicate that underfeeding (
<70% of energy expenditure [EE]) during the acute phase of critical illness (first 7 days of intensive care unit [ICU] admission) may not be harmful and could instead promote autophagy and prevent overfeeding in light of endogenous energy production. However, the optimal energy target during this period is unclear and full starvation is unlikely to be beneficial. There are limited data regarding the effects of prolonged underfeeding on clinical outcomes in critically ill patients, but recent studies show that oral food intake is suboptimal both in the ICU and following discharge to the acute care setting. It is hypothesized that provision of full nutrition (70-100% of EE) may be important in the recovery phase of critical illness (
>7 days of ICU admission) for promoting recovery and rehabilitation; however, studies on nutritional intervention delivered from ICU admission through hospital discharge are needed. The aim of this review is to provide a narrative synthesis of the existing literature on metabolic alterations experienced during critical illness and the impact of underfeeding on clinical outcomes in the critically ill adult patient.
文献关键词：
Critical illness;Intensive care unit;Nutrition;Underfeeding
中图分类号：
作者姓名：
Tatucu-Babet Oana A;Ridley Emma J
作者机构：
Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Level 3, 553 St Kilda Road, Melbourne, VIC 3004, Australia;Nutrition Department, Alfred Hospital, Alfred Health, Melbourne, VIC 3004, Australia
文献出处：
引用格式：
[1]Tatucu-Babet Oana A;Ridley Emma J-.How much underfeeding can the critically ill adult patient tolerate?)[J].重症医学（英文）,2022(02):69-77
A类：
underfeeding,overfeeding,Underfeeding
B类：
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AB值：
0.533647
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