Despite continuous progress,the prevention and treatment of human immunodeficiency virus(HIV)/acquired immune deficiency syndrome(AIDS)remain the world's most serious public health challenges.A key problem is the degree of immune function reconstruction after antiretroviral therapy.Antiretroviral therapy has enriched the treatment of HIV/AIDS and improved the present conditions and the life quality of HIV/AIDS patients.However,some patients still fail to achieve normalization of CD4+T lymphocyte counts although persistent virological suppression.These patients are referred to as immunological non-responders,and usually present with severe immunological dysfunction.To date,since the underlying mechanism of incomplete immune reconstitution in HIV/AIDS has not been fully elucidated,remaining to be the focus and difficulties of current research.It is still a challenge to explore a safe,effective,and reliable therapeutic method for immunological non-responders.Due to fewer side effects and lower drug resistance,traditional Chinese medicine is often sought to provide alternative pharmacotherapy for regulating the immunity of immunological non-responders in China.In this review,we aimed at summarizing the latest and most comprehensive information on traditional Chinese medicine therapeutic methods for promoting immune reconstruction.In addition,outlooks and perspectives for possible future research that related are also discussed.

Shao-Xiu Ji;Heng-Yao Zhang;Ting-Jun Wan;Li Wen;Quan-Sheng Feng

College of Basic Medicine,Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China;Yinchuan Hospital of Traditional Chinese Medicine,Yinchuan 750001,China

传统医学研究（英文版）

[1]Shao-Xiu Ji;Heng-Yao Zhang;Ting-Jun Wan;Li Wen;Quan-Sheng Feng-.Role of traditional Chinese medicine in incomplete immune reconstitution of HIV/AIDS:a review)[J].传统医学研究（英文版）,2022(06):1-11

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