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典型文献
Infra-tentorial brain tumor subtypes in children and adults—surgical outcome in an ethnic population with a single regional tertiary center
文献摘要:
Background::To analyze clinically and radiologically the surgical outcome like residual disease, progression of disease, recurrence, disabilities, event-free survival (EFS), and mortality of different infra-tentorial tumor subtypes in children and adults of a strictly non-migratory and ethnic population.Methods::The 410 histologically proved, out of 589, infra-tentorial brain tumor patients were analyzed clinically and by the imaging post-surgically in a single tertiary center for an ethnic region. In this analytico-observational study, retrospectively postoperative records of 589 infra-tentorial brain tumors from November 1998 to December 2018 (20 years) were retrieved, scrutinized, and compiled. The post-operative clinic-radiological records of 410 patients with proved histopathological examination results were included. Statistical law of variance was applied where-ever necessary.Results::The 63.2% of the all 410 operated infra-tentorial brain tumors were males while females predominated in meningiomas and pineoblastomas. About 31.7% infra-tentorial tumors were children (below 18 years). About 54.1% cases were histologically malignant. The residual tumors comprised 40.2% and symptoms of disease-progression occurred in 10.9%. The tumor recurrence occurred in 14.3% while 6.0% patients developed severe disability. The overall mortality was 11.4% but 18.9% in malignant tumors. The event-free survival (EFS) for all the patients was 66.0%, patients with malignancies had 47.7% and benign group had 87.7%.Conclusion::The study, surgical outcome of infra-tentorial brain tumor subtypes in children and adults (approx. 1/3rd of patients being children), conducted in a tertiary center at a remote land-locked location with non-migratory ethnic population as its catchment area, has a significant epidemiological value for the community and the region.
文献关键词:
Infra-tentorial brain tumors;Histological subtypes;Ethnic population;Surgical outcome
作者姓名:
Bhat Abdul Rashid;Wani Muhammed Afzal;Kirmani Altaf Rehman
作者机构:
Department of Neurosurgery, Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Srinagar, Kashmir, India
引用格式:
[1]Bhat Abdul Rashid;Wani Muhammed Afzal;Kirmani Altaf Rehman-.Infra-tentorial brain tumor subtypes in children and adults—surgical outcome in an ethnic population with a single regional tertiary center)[J].中华神经外科杂志(英文),2022(03):160-168
A类:
tentorial,radiologically,analytico,pineoblastomas
B类:
Infra,brain,subtypes,children,adults,outcome,ethnic,population,single,regional,tertiary,center,Background,To,clinically,like,residual,disease,progression,recurrence,disabilities,event,free,survival,EFS,mortality,different,infra,strictly,migratory,Methods,histologically,proved,patients,were,analyzed,by,imaging,surgically,this,observational,study,retrospectively,postoperative,records,tumors,from,November,December,years,retrieved,scrutinized,compiled,histopathological,examination,results,included,Statistical,law,variance,was,applied,where,necessary,Results,operated,while,females,predominated,meningiomas,About,below,cases,malignant,comprised,symptoms,occurred,developed,severe,disability,overall,but,malignancies,had,benign,group,Conclusion,approx,3rd,being,conducted,remote,land,locked,location,its,catchment,area,has,significant,epidemiological,value,community,Histological,Ethnic,Surgical
AB值:
0.433395
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