典型文献
Rapid quantitative analysis of 12 chemical constituents in wild-simulated and cultivated Astragali Radix based on UHPLC-MS
文献摘要：
Objective:Astragali Radix(AR)is one of the most widely used traditional Chinese medicines(TCMs)for tonic,which can be divided into wild-simulated and cultivated AR according to its cultivation method.However,whether cultivated AR can replace wild-simulated AR has always been a concern.Methods:In this study,a rapid,highly sensitive and specific analytical method using ultra-high perfor-mance liquid chromatography tandem mass spectrometry(UHPLC-MS)was developed to quantitatively measure 12 chemical constituents of AR in the different cultivation methods.Results:AR samples were analyzed with a good linear regression relationship(R2,0.9983-0.9995),preci-sions(relative standard deviation(RSD),1.31％-2.36％),repeatability(RSD,2.65％-4.92％),stability(RSD,1.50％-4.05％),and recovery(95.13％-106.52％).Through the determination of AR samples,we found the components of flavonoids in wild-simulated AR were higher than cultivated AR,the saponins in culti-vated AR were higher,the ratio of saponins/flavonoids in cultivated AR was higher than wild-simulated AR.Conclusion:Based on this research,it could provide guidance for the quality control of AR.
文献关键词：
中图分类号：
作者姓名：
Dan Li;Yuetao Liu;Xuemei Qin
作者机构：
Modern Research Center for Traditional Chinese Medicine,Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education,Shanxi University,Taiyuan 030006,China;Shanxi Key Laboratory of Effective Substances Research and Utilization in Traditional Chinese Medicine,Taiyuan 030006,China
文献出处：
引用格式：
[1]Dan Li;Yuetao Liu;Xuemei Qin-.Rapid quantitative analysis of 12 chemical constituents in wild-simulated and cultivated Astragali Radix based on UHPLC-MS)[J].中草药（英文版）,2022(03):464-469
A类：
B类：
Rapid,analysis,chemical,constituents,wild,simulated,cultivated,Astragali,Radix,UHPLC,Objective,most,widely,used,traditional,Chinese,medicines,TCMs,tonic,which,can,divided,into,according,its,cultivation,However,whether,replace,has,always,been,concern,Methods,In,this,study,rapid,highly,sensitive,specific,analytical,using,ultra,perfor,mance,liquid,chromatography,tandem,mass,spectrometry,was,developed,quantitatively,measure,different,methods,Results,samples,were,analyzed,good,linear,regression,relationship,preci,sions,relative,standard,deviation,RSD,repeatability,stability,recovery,Through,determination,found,components,flavonoids,higher,than,saponins,ratio,Conclusion,Based,research,could,provide,guidance,quality,control
AB值：
0.573585
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