典型文献
Three new triterpenoid saponins from Aralia echinocaulis
文献摘要：
Objective:To study the active ingredients in the root bark of Aralia echinocaulis.Methods:Three triterpenoid saponins were separated from the 70％ethanol extracts and purified by col-umn chromatography and their structures were determined by spectroscopic analysis.Compound 1 and 3 were evaluated for antioxidant activity by the in vitro DPPH free radical scavenging ability and the pro-tective effect of OH-induced DNA oxidative damage.Results:Compound 1 was a new type of triterpenoid saponin,named as echinocaulisaglycone 3-O-β-D-glucopyranoside(echinocaulisaponin A),and it had good antioxidant activity.Compound 2 was similar to compound 1,named as 1-hydroxyl-echinocaulisaglycone 3-O-β-D-glucopyranoside(echinocaulis-aponin B).Compound 3 was also a new type of triterpenoid saponin,named as echinocaulisaglycone Ⅱ3-O-α-L-arabinopyranosyl-(1"→4')-β-D-glucopyranosiduronic acid(echinocaulisaponin C),and its antioxidant activity was weaker than compound 1.Conclusion:In this study,three new compounds were discovered and two of them were carried out in vitro anti-oxidation studies,laying the foundation for further research on the treatment of related dis-eases(cardiovascular disease,arthritis,age-related macular degeneration,etc.)through anti-oxidation or quenching free radical function.
文献关键词：
中图分类号：
作者姓名：
Mengyun Yan;Yajia Sun;Ling Ding;Jiuxu Sun;Jingzhu Song;Wenbin Zhou;Lingpeng Pei
作者机构：
Key Laboratory of Ethnic Medicine Ministry of Education,Minzu University of China,Beijing 100081,China
文献出处：
引用格式：
[1]Mengyun Yan;Yajia Sun;Ling Ding;Jiuxu Sun;Jingzhu Song;Wenbin Zhou;Lingpeng Pei-.Three new triterpenoid saponins from Aralia echinocaulis)[J].中草药（英文版）,2022(02):337-341
A类：
echinocaulis,echinocaulisaglycone,echinocaulisaponin,aponin,glucopyranosiduronic
B类：
Three,new,triterpenoid,saponins,from,Aralia,Objective,To,study,active,ingredients,root,bark,Methods,were,separated,ethanol,extracts,purified,by,col,umn,chromatography,their,structures,determined,spectroscopic,analysis,Compound,evaluated,antioxidant,activity,vitro,DPPH,free,radical,scavenging,ability,pro,tective,effect,induced,oxidative,damage,Results,was,type,named,glucopyranoside,had,good,similar,hydroxyl,also,arabinopyranosyl,acid,its,weaker,Conclusion,In,this,three,compounds,discovered,two,them,carried,out,oxidation,studies,laying,foundation,further,research,treatment,related,eases,cardiovascular,disease,arthritis,macular,degeneration,etc,through,quenching,function
AB值：
0.51525
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