OBJECTIVE:To assess the efficacy and safety of ginger-indirect moxibustion for chronic fatigue syndrome(CFS).METHODS:In this central randomized,controlled trial,290 CFS participants were recruited and randomly allocated to group A(ginger-indirect moxibustion plus acupuncture)or group B(acupuncture alone).The study consisted of a treatment period of 8 weeks with a total of 24 treatments(3 sessions per week,every other day),and a follow-up period of 12 weeks.The outcome was measured by Fatigue Severity Scale(FSS),Psychological Health Report(SPHERE),the Self-rating depression scale(SDS)and the Hamilton anxiety scale(HAMA)at baseline,2,4,6,8,12 and 20 weeks.RESULTS:With the treatment undergoing,the changes of FSS,SPHERE,SDS and HAMA scores in both groups increased gradually,and the effect maintained at the 12th week.Between groups,significantly higher score changes were seen in group A in FSS after 4 weeks treatment(11.94 vs 9.12,95％CI:0.94,4.7)and in SPHERE after 2 weeks treatment(3.7 vs 2.27,95％CI:0.56,2.31).But for SDS and HAMA,the improvement did not differ significantly between groups.No severe adverse events were reported.CONCLUSION:Ginger-indirect moxibustion is a safe and effective intervention to relieve fatigue and accompanying physical symptoms of CFS.

MA Tingting;WU Jie;YANG Lijie;FENG Fen;YANG Huilin;ZHANG Jinhua;ZHONG Yanjin;NING Qing;HUANG Lirong;LIN Youbing;YAN Jue;CHEN Guiquan;HOU Tianshu;WANG Li;REN Yuanfang;TAN Jing

Center of Preventive Medicine,Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China;College of Acupuncture and Tuina,Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China;Department of acupuncture,Center of Preventive Medicine,Affiliated TCM Hospital of Southwest Medical University,Luzhou 646600,China;Center of Preventive Medicine,Chengdu Integrated TCM and Western Medicine Hospital,Chengdu 610021,China;Center of Chinese Evidence-Based Medicine,Sichuan University West China Hospital,Chengdu 610041,China

中医杂志（英文版）

[1]MA Tingting;WU Jie;YANG Lijie;FENG Fen;YANG Huilin;ZHANG Jinhua;ZHONG Yanjin;NING Qing;HUANG Lirong;LIN Youbing;YAN Jue;CHEN Guiquan;HOU Tianshu;WANG Li;REN Yuanfang;TAN Jing-.Ginger-indirect moxibustion plus acupuncture versus acupuncture alone for chronic fatigue syndrome:a randomized controlled trial)[J].中医杂志（英文版）,2022(02):242-249

SPHERE

Ginger,indirect,moxibustion,plus,acupuncture,versus,alone,chronic,fatigue,syndrome,randomized,controlled,trial,OBJECTIVE,To,assess,efficacy,safety,ginger,CFS,METHODS,In,this,central,participants,were,recruited,randomly,allocated,study,consisted,period,weeks,total,treatments,sessions,every,other,day,follow,outcome,was,measured,by,Fatigue,Severity,Scale,FSS,Psychological,Health,Report,Self,rating,depression,scale,SDS,Hamilton,anxiety,HAMA,baseline,RESULTS,With,undergoing,changes,scores,both,groups,increased,gradually,maintained,12th,Between,significantly,higher,seen,after,But,improvement,did,not,differ,between,No,severe,adverse,events,reported,CONCLUSION,effective,intervention,relieve,accompanying,physical,symptoms

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