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典型文献
Biosynthesis of titanium dioxide nanoparticles using Hypericum perforatum and Origanum vulgare extracts and their main components,hypericin and carvacrol as promising antibacterial agents
文献摘要:
OBJECTIVE:To evaluate the anti-bacterial activities of titanium dioxide(TiO2)nanoparticles of Origanum(O.)vulgare and Hypericum(H.)perforatum extracts,carvacrol and hypericin against Staphylococcus(S.)aureus.METHODS:In this study,TiO2 nanoparticles of O.vulgare and H.perforatum extracts,carvacrol and hypericin,were prepared and their antibacterial effects were evaluated against Staphylococcus(S.)aureus.In this study,scanning electron microscope,fourier transform infrared spectrometer,atomic force microscopy,dynamic light scattering and zeta potential were used to investigate the structure of synthesized drugs.RESULTS:Anti-bacterial activity of synthesized NPs was tested by minimum inhibitory concentration(MIC),minimum bactericidal concentration and disc diffusion method.MICs of TiO2-NPs synthesized using O.vulgare,H.perforatum,carvacrol and hypericin and TiO2 were obtained 250,62.5,250,and 250,and 500 μg/mL,respectively.The MBCs for all of these were obtained 1000 μg/mL.CONCLUSION:Green-synthesized of TiO2 nanoparticles provides a promising approach to the use of O.vulgare and H.perforatum,carvacrol and hypericin as novel agents and safer antibacterial compounds,especially anti-S.aureus compounds.
文献关键词:
作者姓名:
Mojtaba Khaksarian;Mahmoud Bahmani;Morovat Taherikalani;Behnam Ashrafi;Mahmoud Rafieian-Kopaei;Naser Abbasi
作者机构:
Department of Physiology and Pharmacology,School of Medicine,Razi Herbal Medicines Research Center,Lorestan University of Medical Sciences,Khorramabad,Iran;Biotechnology and Medicinal Plants Research Center,Ilam University of Medical Sciences,Ilam,Iran;Razi Herbal Medicines Research Center,Lorestan University of Medical Sciences,Khorramabad,Iran;Department of Microbiology,School of Medicine,Lorestan University of Medical Sciences,Khorramabad,Iran;Medical Plants Research Center,Basic Health Sciences Institute,Shahrekord University of Medical Sciences,Shahrekord,Iran;department of Pharmacology,Faculty of Medicine;Ilam University of Medical Sciences,Ilam,Iran
引用格式:
[1]Mojtaba Khaksarian;Mahmoud Bahmani;Morovat Taherikalani;Behnam Ashrafi;Mahmoud Rafieian-Kopaei;Naser Abbasi-.Biosynthesis of titanium dioxide nanoparticles using Hypericum perforatum and Origanum vulgare extracts and their main components,hypericin and carvacrol as promising antibacterial agents)[J].中医杂志(英文版),2022(02):167-175
A类:
hypericin,MBCs
B类:
Biosynthesis,titanium,dioxide,nanoparticles,using,Hypericum,perforatum,Origanum,vulgare,extracts,their,main,components,carvacrol,promising,antibacterial,agents,OBJECTIVE,To,activities,TiO2,against,Staphylococcus,aureus,METHODS,In,this,study,were,prepared,effects,evaluated,scanning,electron,microscope,fourier,transform,infrared,spectrometer,atomic,force,microscopy,dynamic,light,scattering,zeta,potential,used,investigate,structure,synthesized,drugs,RESULTS,Anti,activity,NPs,was,tested,by,minimum,inhibitory,concentration,bactericidal,disc,diffusion,method,MICs,obtained,respectively,these,CONCLUSION,Green,provides,approach,novel,safer,compounds,especially
AB值:
0.473789
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