典型文献
Nucleolar histone deacetylases HDT1,HDT2,and HDT3 regulate plant reproductive development
文献摘要：
Nucleolus is a membrane-less organelle where ribosomes are assembled,and ribosomal RNAs(rRNAs)transcribed and processed.The assembled ribosomes composed of ribosomal proteins and rRNAs syn-thesize proteins for cell survival.In plants,the loss of nucleolar ribosomal proteins often causes game-tophytically or embryonically lethality.The amount of rRNAs are under stringent regulation according to demand and partially switched off by epigenetic modifications.However,the molecular mechanism for the selective activation or silencing is still unclear,and the transcriptional coordination of rRNAs and ribosomal proteins is also unknown.Here,we report the critical role of three Arabidopsis nucleolar proteins HDT1,HDT2,and HDT3 in fertility and transcription of rDNAs and rRNA processing-related genes through histone acetylation.This study highlights the important roles of transcriptional repression of ribosome biogenesis-related genes for plant reproductive development.
文献关键词：
中图分类号：
作者姓名：
Yu Luo;Dong-Qiao Shi;Peng-Fei Jia;Yuan Bao;Hong-Ju Li;Wei-Cai Yang
作者机构：
State Key Laboratory of Molecular Developmental Biology,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,Beijing 100101,China;College of Advanced Agricultural Sciences,University of Chinese Academy of Sciences,Beijing 100049,China
文献出处：
引用格式：
[1]Yu Luo;Dong-Qiao Shi;Peng-Fei Jia;Yuan Bao;Hong-Ju Li;Wei-Cai Yang-.Nucleolar histone deacetylases HDT1,HDT2,and HDT3 regulate plant reproductive development)[J].遗传学报,2022(01):30-39
A类：
Nucleolar,HDT1,HDT2,HDT3,Nucleolus,ribosomes,tophytically,embryonically,rDNAs
B类：
histone,deacetylases,regulate,reproductive,development,membrane,less,organelle,where,are,assembled,ribosomal,rRNAs,transcribed,processed,composed,proteins,syn,thesize,cell,survival,In,plants,loss,nucleolar,often,causes,game,lethality,amount,under,stringent,regulation,according,demand,partially,switched,off,by,epigenetic,modifications,However,molecular,mechanism,selective,activation,silencing,still,unclear,transcriptional,coordination,also,unknown,Here,report,critical,three,Arabidopsis,fertility,processing,related,through,acetylation,This,study,highlights,important,roles,repression,biogenesis
AB值：
0.498373
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