Objective:Emerging evidence shows the effectiveness of speech and language therapy(SLT);however,precise therapeutic parameters remain unclear.Evidence for the use of adjunctive transcranial direct cur-rent stimulation(tDCS)to treat post-stroke aphasia(PSA)is promising;however,the utility of combining tDCS and electroacupuncture(EA)has not yet been analyzed.This study assessed the therapeutic conse-quences of EA and tDCS coupled with SLT in subacute PSA patients who were also undergoing hyperbaric oxygen therapy(HBOT).Methods:A retrospective analysis was conducted on subacute(＜6 months)PSA patients who were divided into three groups:patients who received EA plus tDCS(acupuncture group),patients who under-went tDCS(tDCS group),and patients who experienced conventional therapy(HBOT+SLT).All subjects underwent 21 days of treatment and also received conventional treatment.The aphasia battery of Chinese(ABC)was used to score pre-and post-intervention status.Results:The analysis comprised 238 patients.Cerebral infarction was the most frequent stroke type(137[57.6％]),while motor(66[27.7％])and global aphasia(60[25.2％])were the most common types of apha-sia.After 21 days of intervention,the ABC scores of all patients were improved.The acupuncture group had the highest ABC scores,but only repetition,naming,and spontaneous speech were statistically improved(P＜0.01).Post-hoc tests revealed significant improvement in word retrieval in the acupunc-ture and tDCS groups(P＜0.01,P=0.037),while the acupuncture group had additional significant improvement in spontaneous conversation(P＜0.01).Conclusion:Combining acupuncture and tDCS as an adjuvant therapy for subacute PSA led to significant spontaneous speech and word retrieval improvements.Future prospective,multi-ethnic,multi-center tri-als are warranted.

Samwel Sylvester Msigwa;Yan Li;Xiang-lin Cheng;Fen Cao

Department of Neurology,the Clinical Medicine School of Yangtze University,the First Affiliated Hospital of Yangtze University,Jingzhou 424023,Hubei Province,China;Department of Research and Training,Mirembe National Mental Health Hospital,P.0.Box 910,Dodoma,Tanzania;Department of Rehabilitation,The First Affiliated Hospital of Yangtze University,Jingzhou 424023,Hubei Province,China

结合医学学报（英文版）

[1]Samwel Sylvester Msigwa;Yan Li;Xiang-lin Cheng;Fen Cao-.Combining electroacupuncture and transcranial direct current stimulation as an adjuvant therapy enhances spontaneous conversation and naming in subacute vascular aphasia:A retrospective analysis)[J].结合医学学报（英文版）,2022(03):244-251

HBOT+SLT,apha,acupunc

Combining,electroacupuncture,transcranial,direct,current,stimulation,adjuvant,therapy,enhances,spontaneous,conversation,naming,subacute,vascular,aphasia,retrospective,analysis,Objective,Emerging,evidence,shows,effectiveness,speech,language,however,precise,therapeutic,parameters,remain,unclear,Evidence,adjunctive,tDCS,post,stroke,PSA,promising,utility,combining,EA,not,yet,been,analyzed,This,study,assessed,conse,quences,coupled,patients,who,were,also,undergoing,hyperbaric,oxygen,Methods,was,conducted,months,divided,into,three,groups,received,plus,experienced,conventional,All,subjects,underwent,days,treatment,battery,Chinese,ABC,used,intervention,status,Results,comprised,Cerebral,infarction,most,frequent,while,motor,global,common,types,After,scores,improved,had,highest,but,only,repetition,statistically,Post,hoc,tests,revealed,significant,word,retrieval,additional,Conclusion,improvements,Future,prospective,multi,ethnic,center,are,warranted

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