典型文献
Stable mechanical fixation in a bionic osteochondral scaffold considering bone growth
文献摘要：
In the field of tissue engineering,there is sig-nificant subsidence of the porous design scaffold several months after implantation.To avoid stress shielding and stimulate bone and cartilage ingrowth,high scaffold porosity is needed to diminish the mechanical properties of the scaffold.The closer the mechanical properties of the scaffold are to those of surrounding tissues,the better biological properties it will get.Besides,adequate mechanical stability is needed as the scaffold needs to be well fixed in the target area and it will endure load after surgery.Evaluating the mechanical fixation of the scaffold at the initial stage and the long-term performance of a scaffold for in vivo study is hard,as no facility can be put into the target area for the friction test.This study inves-tigated the mechanical stability of the biomimetic scaffold at the initial stage of implantation by finite element anal-ysis(FEA).According to in vivo study,scaffold could not maintain its original position and would sink 1-2 mm in the target area.The simulation results suggested that mechanical loading is not the main reason for scaffold subsidence.
文献关键词：
中图分类号：
作者姓名：
Jian Zhou;Hao Huang;Li-Jing Wang;Maryam Tamaddon;Chao-Zong Liu;Zi-Yu Liu;Teng-Bo Yu;Ying-Ze Zhang
作者机构：
Department of Orthopaedic Surgery,Qingdao Municipal Hospital,Qingdao University,Qingdao 266071,China;Department of Sports Medicine,Affiliated Hospital of Qingdao University,Qingdao 266000,China;Division of Surgery&Interventional Science,University College London,Royal National Orthopaedic Hospital,London HA7 4LP,UK;School of Aeronautic Science and Engineering,Beihang University,Beijing 100191,China;School of Engineering Medicine,Beihang University,Beijing 100191,China
文献出处：
引用格式：
[1]Jian Zhou;Hao Huang;Li-Jing Wang;Maryam Tamaddon;Chao-Zong Liu;Zi-Yu Liu;Teng-Bo Yu;Ying-Ze Zhang-.Stable mechanical fixation in a bionic osteochondral scaffold considering bone growth)[J].稀有金属（英文版）,2022(08):2711-2718
A类：
ingrowth
B类：
Stable,mechanical,fixation,bionic,osteochondral,scaffold,considering,bone,In,field,engineering,there,nificant,subsidence,porous,design,several,months,after,implantation,To,avoid,stress,shielding,stimulate,cartilage,high,porosity,needed,diminish,properties,closer,those,surrounding,tissues,better,biological,will,Besides,adequate,stability,needs,well,fixed,target,area,endure,surgery,Evaluating,initial,stage,long,term,performance,vivo,study,hard,facility,put,into,friction,test,This,inves,tigated,biomimetic,by,finite,element,anal,ysis,FEA,According,could,not,maintain,its,original,position,would,sink,simulation,results,suggested,that,loading,reason
AB值：
0.53085
相似文献
机标中图分类号，由域田数据科技根据网络公开资料自动分析生成，仅供学习研究参考。
