典型文献
Angiotensin I converting enzyme (ACE) inhibitory activity and antihypertensive effects of rice peptides
文献摘要：
In this paper, the antihypertension effect of rice peptide (RP) was studied. With spontaneously hypertensive rats (SHR) and Wistar Kyoto (WKY) as the research objects, RP disposable gastric and long-term gastric irrigation experiments were carried out and systolic blood pressure (SBP) was measured. At the end of the long-term gastric irrigation experiment, the content of nitric oxide (NO), angiotensin-converting enzyme (ACE), angiotensin Ⅱ(Ang Ⅱ) and renin in the plasma and the activity of ACE were determined. The results showed that RP could reduce systolic pressure of SHR and had time-dose dependence while high-dose RP significantly reduced systolic pressure by 24.6 and 17.2 mmHg, respectively after a single and long-term gastric irrigation test. RP also could inhibit the activity of ACE and increase the release of NO. These results suggested that the decompression mechanism of RP is likely to be related to the regulation of the renin-angiotensin system (RAS) and NO.
文献关键词：
中图分类号：
作者姓名：
Jingjing Dong;Shen Wang;Xiaoyao Yin;Min Fang;Zhiyong Gong;Yongning Wu
作者机构：
Key Laboratory for Deep Processing of Major Grain and Oil of Ministry of Education,College of Food Science and Engineering,Wuhan Polytechnic University,Wuhan 430023,China.;HC Key Laboratory of Food Safety Risk Assessment,Food Safety Research Unit 2019RU014 of Chinese Academy of Medical Science,China National Center for Food Safety Risk Assessment,Beijing 100021,China
文献出处：
引用格式：
[1]Jingjing Dong;Shen Wang;Xiaoyao Yin;Min Fang;Zhiyong Gong;Yongning Wu-.Angiotensin I converting enzyme (ACE) inhibitory activity and antihypertensive effects of rice peptides)[J].食品科学与人类健康（英文）,2022(06):1539-1543
A类：
antihypertension
B类：
Angiotensin,converting,enzyme,ACE,inhibitory,activity,antihypertensive,effects,rice,peptides,In,this,paper,RP,was,studied,With,spontaneously,rats,SHR,Wistar,Kyoto,WKY,research,objects,disposable,gastric,long,irrigation,experiments,were,carried,out,systolic,blood,pressure,SBP,measured,At,content,nitric,oxide,angiotensin,renin,plasma,determined,results,showed,that,could,had,dose,dependence,while,high,significantly,reduced,by,mmHg,respectively,after,single,test,also,increase,release,These,suggested,decompression,mechanism,likely,be,related,regulation,system,RAS
AB值：
0.532355
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